Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 3/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6163869 | 0.87 | POLB (0.45) | ADRA1DCYP19A1CYP11B1CYP11B2KLKB1 | |
| SCHEMBL7105122 | 0.85 | KLKB1 (0.39) | BRD4SIRT2SIRT1ADRA1DCYP19A1 | |
| SCHEMBL7101493 | 0.85 | CACNA1F (0.41) | BRD4SIRT2SIRT1ADRA1DCYP19A1 | |
| SCHEMBL6170882 | 0.83 | MAPT (0.45) | ADRA1DKLKB1KLK1 | |
| SCHEMBL6164249 | 0.83 | POLB (0.40) | BRD4ADRA1DCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL7101526 | 0.82 | CYP19A1 (0.43) | BRD4SIRT2SIRT1ADRA1DCYP19A1 | |
| SCHEMBL7102332 | 0.82 | KLKB1 (0.39) | BRD4SIRT2SIRT1ADRA1DCYP19A1 | |
| SCHEMBL7108857 | 0.82 | POLB (0.46) | ADRA1DCYP19A1CYP11B1CYP11B2KLKB1 | |
| SCHEMBL7105719 | 0.82 | POLB (0.47) | BRD4ADRA1DCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6165929 | 0.81 | ADRA1D (0.52) | BRD4SIRT2SIRT1KDM1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | LG CHEM INVESTMENT LTD. (KR) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065176-A1 | Factor xa inhibitors with aryl-amidines and derivatives, and prodrugs thereof | F2, F12, TFPI | BRD4 2818/4885SIRT2 1626/4885SIRT1 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.