Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.76 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL139430 | 0.87 | — | — | |
| SCHEMBL1190707 | 0.87 | HDAC8 (0.52) | HDAC8GRM5FFAR1PIK3CAMTOR | |
| Hydrochloric Acid SCHEMBL1190733 | 0.85 | — | — | |
| SCHEMBL15283861 | 0.82 | HDAC8 (0.46) | HDAC8FFAR1KEAP1MAPTCA12 | |
| SCHEMBL12873263 | 0.78 | APP (0.52) | HDAC8GRM5FFAR1PIK3CAMTOR | |
| SCHEMBL1820120 | 0.76 | HDAC8 (0.58) | HDAC8GRM5FFAR1PIK3CAMTOR | |
| SCHEMBL1649302 | 0.73 | HDAC8 (0.55) | HDAC8GRM5FFAR1PIK3CAMTOR | |
| SCHEMBL140223 | 0.73 | HDAC8 (0.71) | HDAC8KEAP1LMNAMAPTCA12 | |
| Ammonia Solution, Strong SCHEMBL7107393 | 0.71 | HDAC8 (0.38) | HDAC8GRM5FFAR1PIK3CAMTOR | |
| SCHEMBL1306534 | 0.70 | HDAC8 (0.50) | HDAC8FFAR1KEAP1MAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144423-B1 | BIS-TERPYRIDINE-PLATINUM(II) COMPLEXES | ISIS INNOVATION (GB) | 2003-10-22 | — | — | EP | disclosed |