SCHEMBL7108436

SCHEMBL7108436

Cc1ccccc1C(O)(c1ccccc1C)C(N)Cc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.60
LMNA P02545 1/20 0.60
MAPK1 P28482 1/20 0.60
SLC6A2 P23975 2/20 0.44
TAAR1 Q96RJ0 2/20 0.44
MAOA P21397 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
SCN4A P35499 2/20 0.43
EPHX1 P07099 1/20 0.42
ANPEP P15144 3/20 0.42
CYP2D6 P10635 1/20 0.42
ALPI P09923 1/20 0.41
PKM P14618 1/20 0.41
PTGS1 P23219 1/20 0.41
XIAP P98170 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7681343 1.00 KDM4E (0.60) KDM4ELMNAMAPK1SLC6A2TAAR1
SCHEMBL1153708 0.80 KDM4E (0.55) KDM4ELMNAMAPK1SLC6A2TAAR1
SCHEMBL11161210 0.80 KDM4E (0.55) KDM4ELMNAMAPK1SLC6A2TAAR1
SCHEMBL295340 0.80 KDM4E (0.55) KDM4ELMNAMAPK1SLC6A2TAAR1
SCHEMBL6577104 0.79 KDM4E (0.58) KDM4ELMNAMAPK1SLC6A2TAAR1
SCHEMBL7106018 0.78 LNPEP (0.41) KDM4ELMNAMAPK1MAOAANPEP
SCHEMBL7680886 0.78 LNPEP (0.41) KDM4ELMNAMAPK1MAOAANPEP
SCHEMBL11682981 0.77 KDM4E (0.53) KDM4ELMNAMAPK1SLC6A2TAAR1
SCHEMBL295381 0.77 KDM4E (0.53) KDM4ELMNAMAPK1SLC6A2TAAR1
SCHEMBL1262139 0.77 KDM4E (0.96) KDM4ELMNAMAPK1SLC6A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0942010-B1 Transition metal compounds, catalyst components and catalysts for olefin polymerization, and process for producing olefinic polymer SUMITOMO CHEMICAL CO (JP) 2003-06-18 EP disclosed
US-6500909-B2 CONTAINING NICKEL, PALLADIUM, RHODIUM, RUTHENIUM, OR COBALT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-12-31 US disclosed
US-6410741-B1 INSECTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-20010027162-A1 Transition metal compound, catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefinic polymer HIRAHATA WATARU (JP) 2001-10-04 US disclosed
US-6242377-B1 POLYMERIZATION IN PRESENCE OF BISOXAZOLINE WITH NICKEL, COBALT, PALLADIUM, RHODIUM, RUTHENIUM, ALUMINUM AND BORON COMPLEXES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-05 US disclosed
US-6072081-A Optically active bisoxazoline compounds, production and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-06-06 US disclosed
EP-0942010-A1 Transition metal compounds, catalyst components and catalysts for olefin polymerization, and process for producing olefinic polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-15 EP disclosed