Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.56 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108624 | 0.85 | ADRB2 (0.63) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838432 | 0.80 | ADRB2 (0.85) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838557 | 0.80 | ADRB2 (0.85) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3838435 | 0.80 | ADRB2 (0.85) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7108622 | 0.75 | ADRB2 (0.53) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13708431 | 0.73 | ADRB2 (0.52) | ADRB2ADRB1ADRB3C5AR1 | |
| SCHEMBL3843666 | 0.71 | ADRB2 (1.00) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3843145 | 0.71 | ADRB2 (1.00) | ADRB2ADRB1ADRB3 | |
| SCHEMBL3843146 | 0.71 | ADRB2 (1.00) | ADRB2ADRB1ADRB3 | |
| SCHEMBL13618087 | 0.70 | ADRB2 (0.69) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446379-A1 | ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONISTS | Theravance, Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003042164-A1 | ARYL ANILINE BETA-2 ADRENERGIC RECEPTOR AGONISTS | THERAVANCE, INC (US) | 2003-05-22 | — | — | WO | disclosed |