Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31255983 | 0.83 | KIF11 (0.34) | BRD4CREBBPTSHRNPC1LMNA | |
| SCHEMBL7113134 | 0.82 | BRD4 (0.32) | BRD4CREBBP | |
| SCHEMBL27577744 | 0.82 | BRD4 (0.33) | BRD4CREBBPTSHRNPC1LMNA | |
| SCHEMBL29773661 | 0.81 | TSHR (0.36) | BRD4CREBBPTSHRNPC1LMNA | |
| SCHEMBL22401709 | 0.81 | BRD4 (0.34) | BRD4CREBBPTSHRNPC1LMNA | |
| SCHEMBL28723738 | 0.81 | BRD4 (0.34) | BRD4CREBBPTSHRNPC1LMNA | |
| SCHEMBL21002295 | 0.81 | TSHR (0.36) | BRD4CREBBPTSHRNPC1LMNA | |
| SCHEMBL22418974 | 0.81 | BRD4 (0.34) | BRD4CREBBPTSHRNPC1LMNA | |
| SCHEMBL7033068 | 0.81 | BRD4 (0.34) | BRD4CREBBPTSHRNPC1LMNA | |
| SCHEMBL4866427 | 0.81 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620953-B1 | Complexing dimethylbis(2-methyl-4,5-benzoindenyl)silane with transition metal compounds such as 2,4-di-tert-butylphenoxide, zirconium monochloride, to form polymerization catalysts | BASSELL POLYOLEFINE GMBH (DE) | 2003-09-16 | — | — | US | disclosed |
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | disclosed |