Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105419 | 0.85 | KMT2A (0.55) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7108870 | 0.81 | PPARG (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL16817792 | 0.80 | ALDH1A1 (0.56) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7111208 | 0.79 | ALDH1A1 (0.63) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7106419 | 0.79 | KMT2A (0.57) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7106421 | 0.78 | ALDH1A1 (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7106301 | 0.78 | ALDH1A1 (0.54) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL21665206 | 0.76 | MEN1 (0.84) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL7111223 | 0.76 | SOAT1 (0.51) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL3806017 | 0.76 | MEN1 (0.73) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1348700-A2 | Composition and method for dyeing dye-susceptible material | Wella Aktiengesellschaft (DE) | 2003-10-01 | — | — | EP | disclosed |