Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705191 | 0.85 | HIF1A (0.52) | HIF1APTGS2LMNAMAPTP2RX7 | |
| SCHEMBL6156221 | 0.85 | HIF1A (0.52) | HIF1APTGS2LMNAMAPTP2RX7 | |
| SCHEMBL6155877 | 0.85 | HIF1A (0.48) | HIF1APTGS2LMNAMAPT | |
| SCHEMBL6155881 | 0.85 | HIF1A (0.48) | HIF1APTGS2LMNAMAPT | |
| SCHEMBL6155883 | 0.85 | HIF1A (0.48) | HIF1APTGS2LMNAMAPT | |
| SCHEMBL6158790 | 0.82 | HIF1A (0.44) | HIF1A | |
| SCHEMBL6155943 | 0.82 | HIF1A (0.44) | HIF1A | |
| SCHEMBL6158168 | 0.78 | HIF1A (0.48) | HIF1APTGS2NR1H4LMNAADAM17 | |
| SCHEMBL6156945 | 0.78 | HIF1A (0.48) | HIF1APTGS2NR1H4LMNAADAM17 | |
| SCHEMBL6156508 | 0.78 | HIF1A (0.48) | HIF1APTGS2NR1H4LMNAADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286955-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6348627-B1 | CONTROLLING PHYTOPATHOGENIC FUNGI | DOW AGROSCIENCES LLC | 2002-02-19 | — | — | US | disclosed |
| WO-2001087826-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 2001-11-22 | — | — | WO | disclosed |