Phenanthridine

Phenanthridine

SCHEMBL7108915

c1cc[nH]c1.c1ccc2c(c1)cnc1ccccc12

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 2/20 0.77
KDM4E B2RXH2 1/20 0.77
TOP2A P11388 1/20 0.46
CYP3A4 P08684 1/20 0.46
PDE10A Q9Y233 1/20 0.42
CYP1A2 P05177 2/20 0.41
ALDH1A1 P00352 1/20 0.40
PARP1 P09874 1/20 0.40
PRKCI P41743 1/20 0.40
PDE4B Q07343 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
RECQL P46063 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TLR7 Q9NYK1 2/20 0.39
ADORA3 P0DMS8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenanthridine SCHEMBL9106884 0.88 GPR3 (1.00) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL30914262 0.88 GPR3 (1.00) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL30823553 0.88 GPR3 (1.00) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL8666 0.88 GPR3 (1.00) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL23003530 0.86 GPR3 (0.95) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL3702845 0.86 GPR3 (0.95) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL460289 0.86 GPR3 (0.95) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL2421052 0.86 GPR3 (0.95) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL8505090 0.86 GPR3 (0.95) GPR3KDM4ETOP2ACYP3A4PDE10A
Phenanthridine SCHEMBL2422346 0.86 GPR3 (0.95) GPR3KDM4ETOP2ACYP3A4PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115010717-B Full-synthesis preparation method of lycorine (+ -) -alpha-lycorane 宁夏大学 2023-11-03 CN disclosed
CN-110746422-B Organic compound, high polymer, mixture, composition and organic electronic device thereof 广州华睿光电材料有限公司 2023-01-10 CN disclosed
CN-115010717-A Complete synthesis preparation method of lycorine (+/-) -alpha-lycorane 宁夏大学 2022-09-06 CN disclosed
CN-110746422-A Organic compound, high polymer, mixture, composition and organic electronic device thereof 广州华睿光电材料有限公司 2020-02-04 CN disclosed
US-20030097679-A1 Production of ascorbic acid in plants BAUW GUY JEROME CORNEEL (BE) 2003-05-22 US disclosed
US-6469149-B1 CDNA ENCODING A POLYPEPTIDE HAVING L-GALACTONO-GAMMA-LACTONE DEHYDROGENASE ACTIVITY; EXPRESSION VECTORS; USE IN PRODUCTION OF TRANSGENIC PLANTS, BIOSYNTHESIS OF VITAMIN C VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIES (BE) 2002-10-22 US disclosed
EP-0979287-A2 PRODUCTION OF ASCORBIC ACID IN PLANTS Vlaams Interuniversitair Instituut voor Biotechnologie vzw. (BE) 2000-02-16 EP disclosed
WO-1998050558-A2 PRODUCTION OF ASCORBIC ACID IN PLANTS VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE (BE) 1998-11-12 WO disclosed