Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7104856 | 1.00 | CCR2 (0.73) | CCR2 | |
| SCHEMBL3890055 | 0.91 | CCR2 (0.84) | CCR2 | |
| SCHEMBL3890049 | 0.91 | CCR2 (0.84) | CCR2 | |
| SCHEMBL3890044 | 0.91 | CCR2 (0.84) | CCR2 | |
| SCHEMBL3892968 | 0.86 | CCR2 (0.71) | CCR2 | |
| SCHEMBL6029434 | 0.86 | CCR2 (0.71) | CCR2 | |
| SCHEMBL3888763 | 0.85 | CCR2 (0.67) | CCR2 | |
| SCHEMBL3888755 | 0.85 | CCR2 (0.67) | CCR2 | |
| SCHEMBL3888759 | 0.85 | CCR2 (0.67) | CCR2 | |
| SCHEMBL3887216 | 0.84 | CCR2 (1.00) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343751-A2 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002060859-A2 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-08 | — | — | WO | disclosed |