Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109591 | 1.00 | TBXA2R (0.38) | TBXA2RAKR1C4AKR1C3AKR1C2FFAR1 | |
| SCHEMBL7109597 | 1.00 | TBXA2R (0.38) | TBXA2RAKR1C4AKR1C3AKR1C2FFAR1 | |
| SCHEMBL7113278 | 0.77 | PTGER2 (0.43) | TBXA2RALDH1A1 | |
| SCHEMBL7113174 | 0.75 | TBXA2R (0.42) | TBXA2RAKR1C4AKR1C3AKR1C2FFAR1 | |
| SCHEMBL7113170 | 0.75 | TBXA2R (0.42) | TBXA2RAKR1C4AKR1C3AKR1C2FFAR1 | |
| SCHEMBL7113276 | 0.70 | PTGER2 (0.45) | TBXA2RALDH1A1 | |
| SCHEMBL2356962 | 0.69 | TBXA2R (0.33) | TBXA2R | |
| SCHEMBL7111755 | 0.67 | CTSK (0.32) | MAPT | |
| SCHEMBL28467274 | 0.66 | TBXA2R (0.32) | TBXA2R | |
| SCHEMBL9326867 | 0.61 | CHRM2 (0.36) | ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1048643-B1 | Process for the preparation of chiral epoxides | FIRMENICH & CIE (CH) | 2003-10-22 | — | — | EP | disclosed |
| US-6262288-B1 | Process for the preparation of chiral epoxides | FIRMENICH SA (CH) | 2001-07-17 | — | — | US | disclosed |
| EP-1048643-A1 | Process for the preparation of chiral epoxides | FIRMENICH SA (CH) | 2000-11-02 | — | — | EP | disclosed |