Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HBB | P68871 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | HPRT1 | P00492 | 13/20 | 0.56 |
| ▸ | PNP | P00491 | 4/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL710973 | 1.00 | MEN1 (0.65) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL7229533 | 0.93 | MEN1 (0.59) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL7228781 | 0.93 | MEN1 (0.59) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL14595282 | 0.91 | MEN1 (0.68) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL711557 | 0.90 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL8447226 | 0.90 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL711556 | 0.90 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL711558 | 0.90 | MEN1 (0.70) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL712496 | 0.90 | MEN1 (0.60) | MEN1KMT2AHBBMAPK1PDE3A | |
| SCHEMBL712497 | 0.90 | MEN1 (0.60) | MEN1KMT2AHBBMAPK1PDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124609-B2 | Acyclic nucleoside derivatives | MEDIVIR AB (SE) | 2012-02-28 | — | — | US | claimed |