Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 5/20 | 0.57 |
| ▸ | MMP9 | P14780 | 2/20 | 0.57 |
| ▸ | MMP8 | P22894 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 1/20 | 0.53 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.53 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112524 | 0.97 | RAB9A (0.61) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| SCHEMBL24295312 | 0.79 | RAB9A (0.76) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| SCHEMBL366824 | 0.78 | RAB9A (0.81) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| SCHEMBL29474819 | 0.78 | RAB9A (0.81) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| SCHEMBL7108926 | 0.77 | MAPT (0.49) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| SCHEMBL7106230 | 0.77 | MAPT (0.47) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| SCHEMBL24295138 | 0.77 | RAB9A (0.79) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| SCHEMBL13049169 | 0.76 | RAB9A (0.71) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| SCHEMBL2242816 | 0.76 | KDM4E (1.00) | RAB9ANPC1KDM4ESMN1; SMN2PKM | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL27949942 | 0.75 | RAB9A (0.72) | RAB9ANPC1KDM4ESMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0812319-B9 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RES VENTURES LTD (GB) | 2003-10-08 | — | — | EP | disclosed |
| EP-0812319-B1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RES VENTURES LTD (GB) | 2002-07-10 | — | — | EP | disclosed |
| US-6034246-A | ANTICANCER AGENT | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-03-07 | — | — | US | disclosed |
| EP-0812319-A1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1997-12-17 | — | — | EP | disclosed |
| WO-1996026932-A1 | 2-ARYLBENZAZOLE COMPOUNDS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-09-06 | — | — | WO | disclosed |