Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.45 |
| ▸ | HTR2B | P41595 | 6/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556366 | 0.80 | HTR2A (0.40) | HTR2CHTR2APARP1DRD2 | |
| SCHEMBL6556360 | 0.80 | HTR2A (0.40) | HTR2CHTR2APARP1DRD2 | |
| SCHEMBL1047199 | 0.77 | HTR2C (0.42) | HTR2CHTR2BHTR2A | |
| SCHEMBL10407186 | 0.77 | PARP1 (0.50) | HTR2CHTR2BHTR2APARP1 | |
| SCHEMBL18494344 | 0.77 | PARP1 (0.46) | HTR2CHTR2BHTR2APARP1PARP3 | |
| SCHEMBL29613747 | 0.77 | HTR2C (0.42) | HTR2CHTR2BHTR2A | |
| SCHEMBL12405330 | 0.73 | S100A4 (0.47) | HTR2CHTR2BHTR2APARP1PARP3 | |
| SCHEMBL27723083 | 0.71 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL2021584 | 0.71 | PARP3 (0.48) | HTR2CHTR2BHTR2APARP1PARP3 | |
| SCHEMBL2021580 | 0.71 | PARP3 (0.48) | HTR2CHTR2BHTR2APARP1PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011281-A1 | TREATMENT OF ATTENTION DEFICIT HYPERACTIVITY DISORDER OR ATTENTION DEFICIT DISORDER | VERNALIS RESEARCH LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |