Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | ELANE | P08246 | 3/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17312298 | 0.98 | MAPT (0.59) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL129661 | 0.98 | MAPT (0.59) | MAPTGAAL3MBTL1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5983442 | 0.95 | MAPT (0.57) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL10670489 | 0.95 | MAPT (0.57) | MAPTGAAL3MBTL1NPC1RAB9A | |
| Naphthalene SCHEMBL11144924 | 0.93 | MAPT (0.55) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL11769878 | 0.88 | MAPT (0.50) | MAPTGAAL3MBTL1NPC1RAB9A | |
| Formic Acid SCHEMBL28267340 | 0.86 | MAPT (0.53) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL11036875 | 0.83 | MAPT (0.50) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL31043101 | 0.81 | GAA (0.51) | MAPTGAAL3MBTL1NPC1RAB9A | |
| SCHEMBL31043074 | 0.81 | L3MBTL1 (0.47) | MAPTGAAL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087052-A2 | DYES AND FLUORESCENT COMPOUNDS | TERPETSCHNIG EWALD A (US) | 2003-10-23 | — | — | WO | disclosed |