SCHEMBL711003

SCHEMBL711003

O=C1C=CC(=O)N1c1ccccc1Br

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 15/20 1.00
TLR9 Q9NR96 2/20 0.70
FAAH O00519 5/20 0.52
ALDH1A1 P00352 1/20 0.47
HSP90AA1 P07900 1/20 0.47
PKM P14618 1/20 0.47
CCR6 P51684 1/20 0.47
ATM Q13315 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29510698 1.00 MGLL (1.00) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL121404 0.83 TLR9 (1.00) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL29377102 0.83 TLR9 (1.00) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL5074360 0.83 MGLL (0.70) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL28883301 0.79 MGLL (0.66) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL9084081 0.79 TLR9 (0.73) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL15434896 0.78 MGLL (0.62) MGLLTLR9ALDH1A1TDP1GSK3A
SCHEMBL6832688 0.76 TLR9 (0.76) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL3778737 0.76 MGLL (0.61) MGLLTLR9FAAHALDH1A1HSP90AA1
SCHEMBL28883423 0.75 MGLL (0.60) MGLLTLR9FAAHALDH1A1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110418783-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-10-04 CN claimed
CN-110198927-B Process for purifying N-substituted maleimides 株式会社LG化学 2022-08-12 CN claimed
EP-3636634-B1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEMICAL LTD (KR) 2022-06-22 EP claimed
CN-109071432-B Synthesis method of N-substituted maleimide by using solid acid catalyst 株式会社LG化学 2022-04-12 CN claimed
EP-3578544-B1 METHOD FOR PURIFYING N-SUBSTITUTED MALEIMIDE LG CHEMICAL LTD (KR) 2020-12-30 EP claimed
EP-3360906-B1 HIGHLY HEAT-RESISTANT STYRENE-ACRYLONITRILE RESIN AND PREPARATION METHOD THEREFOR LG CHEMICAL LTD (KR) 2020-11-18 EP claimed
US-10696766-B2 Styrene-acrylonitrile resin with high thermal resistance and method for producing the same LG CHEM, LTD. (KR) 2020-06-30 US claimed
CN-108290984-B High heat resistance styrene-acrylonitrile resin and preparation method thereof 株式会社LG化学 2020-04-07 CN claimed
EP-3421451-B1 METHOD FOR PRODUCING N-SUBSTITUTED MALEIMIDE USING SOLID ACID CATALYST LG CHEMICAL LTD (KR) 2020-03-25 EP claimed
CN-110724154-A Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof 湖北科技学院 2020-01-24 CN claimed
EP-0194384-B1 THERMODYNAMICALLY MISCIBLE POLYMER COMPOSTIONS ARCO CHEMICAL TECHNOLOGY, INC. (US) 1990-03-14 EP claimed
US-4845155-A PEROXIDATION ARCO CHEMICAL TECHNOLOGY, INC. (US) 1989-07-04 US claimed
EP-0284301-A2 Alkyl vinyl ether/N-arylmaleimide copolymer containing polymer alloy ARCO Chemical Technology, L.P. (US) 1988-09-28 EP claimed
US-4764558-A Alkyl vinyl ether/N-arylmaleimide copolymer containing polymer alloy ARCO CHEMICAL COMPANY (US) 1988-08-16 US claimed
EP-0220909-A2 Thermodynamically miscible polymer composition ARCO Chemical Technology, L.P. (US) 1987-05-06 EP claimed
EP-0196872-A2 Molding composition containing functionalised thermoplastic rubber and method ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-10-08 EP claimed
EP-0194384-A1 Thermodynamically miscible polymer compostions ARCO CHEMICAL TECHNOLOGY, INC. (US) 1986-09-17 EP claimed
US-4605700-A OLEFIN-MALEIMIDE COPOLYMER AND ACRYLONITRILE-VINYL AROMATIC COPOLYMER BLEND HAVING A SINGLE GLASS TRANSITION TEMPERATURE; MOLDINGS ATLANTIC RICHFIELD COMPANY (US) 1986-08-12 US claimed
US-4588774-A MOLDING MATERIALS, MALEIMIDE MONOMER, GRAFTED SYNTHETIC RUBBERS ATLANTIC RICHFIELD COMPANY (US) 1986-05-13 US claimed
US-4497928-A Moldable polyblend containing poly(arylene sulfide) ATLANTIC RICHFIELD COMPANY (US) 1985-02-05 US claimed