Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001041 | 0.82 | NPC1 (0.43) | NPC1RAB9AKMT2ATBXAS1HDAC1 | |
| SCHEMBL1261544 | 0.80 | — | — | |
| SCHEMBL29163121 | 0.79 | NPC1 (0.47) | NPC1RAB9AKMT2ATBXAS1HDAC1 | |
| SCHEMBL1237700 | 0.78 | NPC1 (0.43) | NPC1RAB9AKMT2ATBXAS1HDAC1 | |
| SCHEMBL8782516 | 0.78 | NPC1 (0.40) | NPC1RAB9AKMT2ATBXAS1FDPS | |
| SCHEMBL28326469 | 0.78 | — | — | |
| SCHEMBL2321138 | 0.78 | — | — | |
| SCHEMBL2876897 | 0.77 | SMN1; SMN2 (0.51) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL262330 | 0.76 | — | — | |
| SCHEMBL8223825 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1473817-A | Process for preparing 1-chloroformyl-3-mesyl imidazolidylone | 山东瑞阳制药有限公司 | 2004-02-11 | — | — | CN | claimed |
| EP-0533244-B1 | Amide-substituted derivatives of spiroindanylcamphorsulfonyl oxytocin antagonists | MERCK & CO INC (US) | 1997-12-17 | — | — | EP | claimed |
| JP-6116243-A | — | — | None | — | — | JP | disclosed |
| JP-4327575-A | — | — | None | — | — | JP | disclosed |
| CN-104387325-B | The synthetic method of the imidazolidinone of 1 chloroformyl, 3 mesyl 2 | 山东鑫泉医药有限公司 | 2017-06-09 | — | — | CN | disclosed |
| CN-102559210-B | Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element | CHI MEI CORP | 2015-07-08 | — | — | CN | disclosed |
| CN-104387325-A | Synthetic method of 1-chloroformyl-3-methylsulfonyl-2-imidazolidone | SHANDONG XINQUAN PHARMACEUTICAL CO LTD | 2015-03-04 | — | — | CN | disclosed |
| CN-102559210-A | Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element | CHI MEI CORP | 2012-07-11 | — | — | CN | disclosed |
| US-20120162588-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT | CHI MEI CORPORATION (TW) | 2012-06-28 | — | — | US | disclosed |
| CN-101585845-B | Preparation process of Mezlocillin | ZHEJIANG JINHUA CONBA BIO PHARM CO LTD | 2011-06-22 | — | — | CN | disclosed |
| CN-101585845-A | Preparation process of Mezlocillin | ZHEJIANG JINHUA CONBA BIOPHARM (CN) | 2009-11-25 | — | — | CN | disclosed |
| US-6313311-B1 | ADRENERGIC STIMULANTS FOR POTENTIATING ANESTHETICS PRIOR TO SURGERY; HYPOTENSIVE AGENTS, ANALGESICS, ANTIISCHEMIC AGENTS; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | ORION CORPORATION (FI) | 2001-11-06 | — | — | US | disclosed |
| CN-1069639-C | Preparation process of 1-chloroformyl-3-mesyl imidazolyl alkyl ketone | YIMENG XINHUA PHARMACEUTICAL F (CN) | 2001-08-15 | — | — | CN | disclosed |
| CN-1068592-C | Imidazole derivatives having affinity for alpha 2 receptors activity | ORION YHTYMAE OY (FI) | 2001-07-18 | — | — | CN | disclosed |
| CN-1239716-A | Preparation process of 1-chloroformyl-3-mesyl imidazolyl alkyl ketone | YIMENG XINHUA PHARMACEUTICAL F (CN) | 1999-12-29 | — | — | CN | disclosed |
| EP-0888309-A1 | IMIDAZOLE DERIVATIVES HAVING AFFINITY FOR ALPHA2 RECEPTORS ACTIVITY | ORION CORPORATION (FI) | 1999-01-07 | — | — | EP | disclosed |
| CN-1198741-A | Imidazole derivatives having affinity for alpha 2 receptor activity | ORION YHTYMAE OY (FI) | 1998-11-11 | — | — | CN | disclosed |
| WO-1997012874-A1 | IMIDAZOLE DERIVATIVES HAVING AFFINITY FOR ALPHA2 RECEPTORS ACTIVITY | Orion-Yhtymä Oy (FI) | 1997-04-10 | — | — | WO | disclosed |
| JP-H06116243-A | PRODUCTION OF 2-ALKYLFORMYLIMIDAZOLE | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1994-04-26 | — | — | JP | disclosed |
| JP-H04327575-A | PRODUCTION OF 2-ALKYL-4-HALOGENO-5-FORMYLIMIDAZOLE | NIPPON SYNTHETIC CHEM IND CO LTD:THE | 1992-11-17 | — | — | JP | disclosed |