Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7114872 | 0.99 | SCN5A (0.49) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| SCHEMBL7115544 | 0.92 | SCN5A (0.49) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7799624 | 0.91 | SCN5A (0.48) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7110340 | 0.90 | SCN5A (0.47) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| SCHEMBL7110564 | 0.85 | SCN5A (0.62) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7109813 | 0.84 | SCN5A (0.61) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| Dimethylamine SCHEMBL7110337 | 0.84 | SCN2A (0.51) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| Dimethylamine SCHEMBL7114875 | 0.83 | SCN2A (0.50) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| Dimethylamine SCHEMBL7115548 | 0.80 | SCN2A (0.50) | SCN5ASCN2AKDM4EHPGDL3MBTL1 | |
| SCHEMBL7111661 | 0.80 | SCN2A (0.54) | SCN5ASCN2AKDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6600072-B2 | Cardiovascular disorders; antiischemic agents; antiarrhythmia agents | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-07-29 | — | — | US | claimed |
| US-20030013760-A1 | Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them | BRENDEL JOACHIM (DE) | 2003-01-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013760-A1 | Substituted 1-naphthoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them | TNNI3, TNNT2, SCN1B | SCN5A 50/4885SCN2A 37/4885KDM4E 3935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.