SCHEMBL711051

SCHEMBL711051

CCC(C)=C(CO)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
FFAR3 O14843 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GRIK1 P39086 2/20 0.37
THRB P10828 1/20 0.35
FNTA P49354 1/20 0.35
FNTB P49356 1/20 0.35
PGGT1B P53609 1/20 0.35
OR51E2 Q9H255 1/20 0.35
GRIA4 P48058 1/20 0.34
GRIK3 Q13003 1/20 0.34
GRIK5 Q16478 1/20 0.34
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17165735 0.83 FFAR3 (0.42) TDP1FFAR3ALDH1A1GRIK1THRB
SCHEMBL28983400 0.83 GRIK1 (0.39) FFAR3GRIK1THRBFNTAFNTB
SCHEMBL3268314 0.83 FFAR3 (0.42) TDP1FFAR3ALDH1A1GRIK1THRB
SCHEMBL28983396 0.83 GRIK1 (0.39) FFAR3GRIK1THRBFNTAFNTB
SCHEMBL10052566 0.77 FFAR3 (0.43) TDP1FFAR3ALDH1A1GRIK1THRB
SCHEMBL6681026 0.77 GRIK1 (0.35) ALDH1A1GRIK1THRBFNTAFNTB
SCHEMBL1537803 0.77 FFAR3 (0.43) TDP1FFAR3ALDH1A1GRIK1THRB
SCHEMBL12521748 0.76 FFAR3 (0.40) TDP1FFAR3ALDH1A1GRIK1THRB
SCHEMBL3628023 0.75
SCHEMBL8767817 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180318473-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2018-11-08 US claimed
EP-3345631-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES Abraxis BioScience, LLC (US) 2018-07-11 EP claimed
EP-3345632-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES Abraxis BioScience, LLC (US) 2018-07-11 EP claimed
US-9954126-B2 Three-dimensional photovoltaic devices including cavity-containing cores and methods of manufacture Q1 NANOSYSTEMS CORPORATION (US) 2018-04-24 US claimed
EP-1861070-B1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2018-01-17 EP claimed
US-20170203012-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2017-07-20 US claimed
US-20160043251-A1 Three-Dimensional Photovoltaic Devices Including Cavity-containing Cores and Methods of Manufacture ACADIA WOODS PARTNERS, LLC 2016-02-11 US claimed
US-20160043253-A1 Methods for Manufacturing Three-Dimensional Metamaterial Devices with Photovoltaic Bristles ACADIA WOODS PARTNERS, LLC 2016-02-11 US claimed
EP-2896412-A1 Drugs with improved hydrophobicity for incorporation in medical devices Abraxis BioScience, LLC (US) 2015-07-22 EP claimed
US-20150190556-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES ABRAXIS BIOSCIENCE LLC (US) 2015-07-09 US claimed
WO-2006020742-A2 MEDICAL DEVICES HAVING NANOPOROUS LAYERS AND METHODS FOR MAKING THE SAME SETAGON, INC. (US) 2006-02-23 WO claimed
US-20050137684-A1 Stent with therapeutically active drug coated thereon PFIZER INC 2005-06-23 US claimed
US-20050085902-A1 Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures,Including delivery using a modified stent CARDINAL HEALTH SWITZERLAND 515 GmbH (CH) 2005-04-21 US claimed
EP-1407726-A1 Local delivery of rapamycin for treatment of proliferative sequelae associated with PTCA procedures, including delivery using a modified stent Cordis Corporation (US) 2004-04-14 EP claimed
US-6585764-B2 Stent with therapeutically active dosage of rapamycin coated thereon CORDIS CORPORATION 2003-07-01 US claimed
EP-0587565-B1 INTRAOCULAR LENS WITH HAPTIC ANCHOR PLATE MEDEVEC LICENSING BV (NL) 1998-08-19 EP claimed
EP-0587565-A4 INTRAOCULAR LENS WITH HAPTIC ANCHOR PLATE. CUMMING STUART J (US) 1995-02-22 EP claimed
EP-0587565-A1 INTRAOCULAR LENS WITH HAPTIC ANCHOR PLATE MEDEVEC LICENSING B.V. (NL) 1994-03-23 EP claimed
WO-1992021304-A1 INTRAOCULAR LENS WITH HAPTIC ANCHOR PLATE CUMMING STUART J (US) 1992-12-10 WO claimed
US-5047051-A Intraocular lens with haptic anchor plate THE NICE TRUST, A TRUST OF THE ISLE OF MAN 1991-09-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170203012-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES MIF, MKI67, ABCB11 TDP1 3471/4885FFAR3 2073/4885ALDH1A1 772/4885
US-20180318473-A1 DRUGS WITH IMPROVED HYDROPHOBICITY FOR INCORPORATION IN MEDICAL DEVICES MIF, MKI67, ABCB11 TDP1 3471/4885FFAR3 2073/4885ALDH1A1 772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.