⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5987355 | 0.77 | — | — | |
| SCHEMBL4601152 | 0.75 | — | — | |
| SCHEMBL16653859 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL29181850 | 0.69 | — | — | |
| SCHEMBL12276842 | 0.68 | GSK3A (0.41) | — | |
| SCHEMBL87616 | 0.67 | GSK3B (0.47) | — | |
| SCHEMBL6209985 | 0.67 | — | — | |
| SCHEMBL29395461 | 0.66 | ATG4B (0.33) | — | |
| SCHEMBL75166 | 0.65 | — | — | |
| SCHEMBL16335043 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111505294-B | Application of artificial antigen of variolothricin in enzyme linked immunosorbent assay kit | 北京望尔生物技术有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-111505294-A | Application of artificial antigen of variolothricin in enzyme linked immunosorbent assay kit | 北京望尔生物技术有限公司 | 2020-08-07 | — | — | CN | claimed |
| EP-3107557-A1 | HYDROPHILIC ANTIBODY-DRUG CONJUGATES | Seattle Genetics, Inc. (US) | 2016-12-28 | — | — | EP | disclosed |
| WO-2015123679-A1 | HYDROPHILIC ANTIBODY-DRUG CONJUGATES | SEATTLE GENETICS, INC. (US) | 2015-08-20 | — | — | WO | disclosed |
| EP-1019722-B1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | ABBOTT LAB (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-1019722-A1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | Abbott Laboratories (US) | 2000-07-19 | — | — | EP | disclosed |
| US-5994143-A | FLUORESCENT CONJUGATES SUITABLE FOR USE IN FLOW CYTOMETRY AND OTHER BIOLOGICAL APPLICATIONS; THE FLUORESCENT CONJUGATES COMPRISE AN ANTIBODY HAVING A POLYMERIC DYE BOUND THERETO | ABBOTT LABORATORIES (US) | 1999-11-30 | — | — | US | disclosed |
| WO-1997028447-A1 | POLYMERIC FLUOROPHORES ENHANCED BY MOIETIES PROVIDING A HYDROPHOBIC AND CONFORMATIONALLY RESTRICTIVE MICROENVIRONMENT | ABBOTT LABORATORIES (US) | 1997-08-07 | — | — | WO | disclosed |