Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 6/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 5/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 5/20 | 0.47 |
| ▸ | CDK2 | P24941 | 5/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 6/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7110928 | 1.00 | CSNK2A1 (0.47) | CSNK2A1CSNK2A2CSNK2BCDK2CCNE1 | |
| SCHEMBL5891718 | 0.88 | FLT3 (0.53) | CSNK2A1CSNK2A2CSNK2BCDK2CCNE1 | |
| SCHEMBL5891707 | 0.88 | FLT3 (0.53) | CSNK2A1CSNK2A2CSNK2BCDK2CCNE1 | |
| SCHEMBL4889912 | 0.87 | MAPKAPK2 (0.55) | CDK2CCNE1PDGFRACDK1PRKCA | |
| SCHEMBL4889926 | 0.87 | MAPKAPK2 (0.55) | CDK2CCNE1PDGFRACDK1PRKCA | |
| SCHEMBL5840603 | 0.84 | CDK1 (0.62) | CSNK2A1CSNK2A2CSNK2BCDK2CCNE1 | |
| SCHEMBL5840595 | 0.84 | CDK1 (0.62) | CSNK2A1CSNK2A2CSNK2BCDK2CCNE1 | |
| SCHEMBL4890517 | 0.83 | PDGFRA (0.49) | CSNK2A1CSNK2A2CSNK2BCDK2CCNE1 | |
| SCHEMBL4890532 | 0.83 | PDGFRA (0.49) | CSNK2A1CSNK2A2CSNK2BCDK2CCNE1 | |
| SCHEMBL4898746 | 0.82 | FLT3 (0.62) | CDK2CCNE1PDGFRACDK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347975-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | Aventis Pharma S.A. (FR) | 2003-10-01 | — | — | EP | claimed |
| WO-2002051843-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | claimed |
| EP-1347975-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | Aventis Pharma S.A. (FR) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002051843-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | disclosed |