SCHEMBL71110

SCHEMBL71110

O=C(O)c1ccc2oc3ccc(C(=O)O)cc3c2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 8/20 0.68
AKR1B1 P15121 1/20 0.54
KDM4E B2RXH2 3/20 0.53
TP53 P04637 2/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MEN1 O00255 1/20 0.53
ALDH1A1 P00352 1/20 0.53
CYP2C9 P11712 1/20 0.53
PTGER1 P34995 1/20 0.53
PTGER3 P43115 1/20 0.53
PTGER2 P43116 1/20 0.53
KMT2A Q03164 1/20 0.53
PTGDR Q13258 1/20 0.53
PIM1 P11309 2/20 0.50
CSNK2A1 P68400 2/20 0.50
STS P08842 1/20 0.50
TSHR P16473 3/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11768568 0.92 TTR (0.65) TTRAKR1B1KDM4ETP53HPGD
SCHEMBL1222307 0.90 TTR (0.78) TTRKDM4EHPGDHSD17B10MEN1
SCHEMBL68189 0.90 TTR (0.83) TTRAKR1B1KDM4ETP53HPGD
SCHEMBL3105380 0.89 TTR (0.84) TTRAKR1B1KDM4ETP53HPGD
Hydrochloric Acid SCHEMBL11749391 0.88 TTR (0.81) TTRAKR1B1KDM4ETP53HPGD
SCHEMBL23693530 0.84 TTR (0.53) TTRAKR1B1KDM4ETP53HPGD
SCHEMBL27147943 0.84 TTR (0.53) TTRAKR1B1KDM4ETP53HPGD
SCHEMBL1259182 0.84 TTR (0.56) TTRAKR1B1KDM4ETP53HPGD
SCHEMBL11322640 0.83 TTR (0.80) TTRAKR1B1KDM4ETP53HPGD
SCHEMBL29826714 0.82 TTR (0.54) TTRAKR1B1KDM4ETP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5756634-A Liquid one component PU stoving enamels HUELS AKTIENGESELLSCHAFT (DE) 1998-05-26 US claimed
EP-0494432-A2 Melt-colored thick and thin yarn BASF CORPORATION (US) 1992-07-15 EP claimed
WO-2022255235-A1 METAL ORGANIC STRUCTURE, GAS-STORING AGENT COMPRISING SAME, AND GAS STORAGE METHOD USING SAME 学校法人立教学院 2022-12-08 WO disclosed
EP-1987193-B1 MOORING LINE DSM IP ASSETS BV (NL) 2016-10-26 EP disclosed
CN-101389807-B Anchor line DSM IP ASSETS BV 2013-01-02 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-20090235629-A1 MOORING LINE DSM IP ASSETS B.V. (NL) 2009-09-24 US disclosed
US-4070342-A HEAT RESISTANCE, COPPER COMPLEX MELT SPINNING ADDITIVE ALLIED CHEMICAL CORPORATION (US) 1978-01-24 US disclosed
US-4045534-A EXTRUDING POLYESTERS OR POLYAMIDES THROUGH A SPINNERET ALLIED CHEMICAL CORPORATION (US) 1977-08-30 US disclosed
US-4031692-A PICK RESISTANT POLYESTER TWIST FIBER INDUSTRIES, INC. (US) 1977-06-28 US disclosed
US-4013694-A CERIA CATALYZEA CONVERSION OF PHENOLS TO DIBENZOFURANS MONSANTO COMPANY (US) 1977-03-22 US disclosed
US-4012546-A ANTIMONY OXIDE OR ZINC BORATE; ALUMINUM HYDROXIDE OR OXIDE AND A LATEX AS BONDING AGENT ALLIED CHEMICAL CORPORATION (US) 1977-03-15 US disclosed
US-3988086-A Melt spinning apparatus with convergence guide ALLIED CHEMICAL CORPORATION (US) 1976-10-26 US disclosed
US-3985926-A POLYESTER AND POLYAMIDE FIBERS INCORPORATED WITH A ZINC COMPOUND ALLIED CHEMICAL CORPORATION (US) 1976-10-12 US disclosed
US-3940544-A Production of polyester yarn ALLIED CHEMICAL CORPORATION (US) 1976-02-24 US disclosed
US-3936253-A Apparatus for melt-spinning synthetic fibers ALLIED CHEMICAL CORPORATION (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TTR 3513/4885AKR1B1 1027/4885KDM4E 717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.