Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238577 | 0.82 | CRHR1 (0.48) | CRHR1PDE10A | |
| SCHEMBL5252287 | 0.80 | CRHR1 (0.47) | CRHR1PDE10A | |
| SCHEMBL3242067 | 0.80 | CRHR1 (0.48) | CRHR1PDE10A | |
| SCHEMBL3247778 | 0.79 | CRHR1 (0.47) | CRHR1PDE10A | |
| SCHEMBL5549998 | 0.78 | CRHR1 (0.47) | CRHR1PDE10A | |
| SCHEMBL5551936 | 0.77 | CRHR1 (0.52) | CRHR1PDE10A | |
| Hydrochloric Acid SCHEMBL6283880 | 0.77 | CRHR1 (0.47) | CRHR1PDE10A | |
| SCHEMBL3244939 | 0.77 | CRHR1 (0.47) | CRHR1PDE10A | |
| SCHEMBL3242643 | 0.77 | CRHR1 (0.49) | CRHR1 | |
| SCHEMBL3246209 | 0.76 | CRHR1 (0.50) | CRHR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425280-A2 | HETERO-BICYCLIC CRF ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003008412-A2 | HETERO-BICYCLIC CRF ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2003-01-30 | — | — | WO | disclosed |