Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | IAPP | P10997 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27643856 | 0.88 | TSHR (0.47) | GABRA1GABRB2TSHRHDAC4HDAC2 | |
| SCHEMBL11284851 | 0.83 | GABRA1 (0.53) | GABRA1GABRB2TSHRHDAC4HDAC2 | |
| SCHEMBL28359972 | 0.83 | GABRA1 (0.35) | GABRA1GABRB2TSHRPOLBMAPK1 | |
| SCHEMBL3959615 | 0.82 | TSHR (0.50) | GABRA1GABRB2TSHRPOLBMAPK1 | |
| SCHEMBL23153080 | 0.82 | TSHR (0.50) | GABRA1GABRB2TSHRPOLBMAPK1 | |
| SCHEMBL27833287 | 0.80 | BID (0.42) | TSHRIAPPHTR1A | |
| SCHEMBL258656 | 0.79 | GABRA1 (0.63) | GABRA1GABRB2TSHRPOLBMAPK1 | |
| Ammonia Solution, Strong SCHEMBL7544347 | 0.77 | GABRA1 (0.61) | GABRA1GABRB2TSHRPOLBMAPK1 | |
| SCHEMBL27494366 | 0.77 | GABRA1 (0.61) | GABRA1GABRB2TSHRPOLBMAPK1 | |
| SCHEMBL9325688 | 0.76 | GABRA1 (0.65) | GABRA1GABRB2TSHRHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1290002-A1 | CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2003-03-12 | — | — | EP | disclosed |
| EP-1175424-A1 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE IN A CATALYST SYSTEM FOR PRODUCING POLYOLEFINS | Basell Polyolefine GmbH (DE) | 2002-01-30 | — | — | EP | disclosed |
| WO-2001090112-A1 | CHEMICAL PRODUCTS SUITED FOR USE AS CO-CATALYSTS, METHOD FOR THE PREPARATION THEREOF AND THEIR USE IN CATALYST SYSTEMS FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-11-29 | — | — | WO | disclosed |
| WO-2000064906-A1 | CHEMICAL COMPOUND, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE IN A CATALYST SYSTEM FOR PRODUCING POLYOLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2000-11-02 | — | — | WO | disclosed |