Malonaldehyde

Malonaldehyde

SCHEMBL7111168

CC(C)C(=O)O.CC(C)C(=O)O.O=CCC=O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.40
GABRR1 P24046 2/20 0.35
SLC7A5 Q01650 2/20 0.35
RNPEP Q9H4A4 1/20 0.35
CYP1A2 P05177 1/20 0.35
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33
MMP13 P45452 1/20 0.33
HTR2A P28223 2/20 0.32
CHRM1 P11229 1/20 0.32
AKR1A1 P14550 1/20 0.32
CHRM3 P20309 1/20 0.32
HTR2C P28335 1/20 0.32
ADRA1A P35348 1/20 0.32
HRH1 P35367 1/20 0.32
DRD3 P35462 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HDAC1 Q13547 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonaldehyde SCHEMBL4014033 1.00 TP53 (0.40) TP53GABRR1SLC7A5RNPEPCYP1A2
Propionaldehyde SCHEMBL28220762 0.82 TDP1 (0.53) TP53GABRR1SLC7A5RNPEPCYP1A2
SCHEMBL31243338 0.81 ALDH1A1 (0.46) TDP1LMNAPTGS1PTGS2GRIK1
SCHEMBL27651305 0.80
SCHEMBL9040306 0.80 TP53 (0.38) TP53GABRR1SLC7A5RNPEPCYP1A2
SCHEMBL6899221 0.80 GABRR1 (0.44) TP53GABRR1SLC7A5TDP1LMNA
Acetaldehyde SCHEMBL8145563 0.78 TP53 (0.47) TP53GABRR1SLC7A5RNPEPCYP1A2
Formic Acid SCHEMBL9619050 0.78 TP53 (0.47) TP53GABRR1SLC7A5RNPEPCYP1A2
Formic Acid SCHEMBL9619062 0.78 TP53 (0.47) TP53GABRR1SLC7A5RNPEPCYP1A2
SCHEMBL11267658 0.78 TP53 (0.47) TP53GABRR1SLC7A5RNPEPCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1103584-B1 Ink compositions containing malonaldehyde bis (dimethylacetal) XEROX CORP (US) 2003-10-29 EP disclosed