Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 4/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107404 | 0.87 | EPOR (0.47) | EPORAKR1C3AKR1C2PTGS1MMP1 | |
| SCHEMBL7109248 | 0.87 | EPOR (0.47) | EPORAKR1C3AKR1C2PTGS1MMP1 | |
| Tert-Butylamine SCHEMBL7109741 | 0.82 | EPOR (0.43) | EPORAKR1C3AKR1C2PTGS1AKR1C1 | |
| SCHEMBL7107759 | 0.80 | MMP1 (0.47) | EPORMMP1MMP2MMP9MMP12 | |
| SCHEMBL7111053 | 0.78 | PPARA (0.50) | EPORPTGS1ALOX5ALOX5APPTGS2 | |
| Tert-Butylamine SCHEMBL7112471 | 0.78 | EPOR (0.46) | EPORPTGS1ALOX5ALOX5APPTGS2 | |
| SCHEMBL7107402 | 0.77 | MAOB (0.49) | EPORPTGS1ALOX5ALOX5APPTGS2 | |
| SCHEMBL10528863 | 0.77 | MMP1 (0.45) | AKR1C3AKR1C2PTGS1AKR1C1MMP1 | |
| SCHEMBL10528875 | 0.77 | MMP1 (0.45) | AKR1C3AKR1C2PTGS1AKR1C1MMP1 | |
| SCHEMBL7105131 | 0.76 | MAOB (0.51) | EPORPTGS1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013639-B1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| EP-1013639-A1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |