SCHEMBL7112097

SCHEMBL7112097

Cc1ccc(C(Cl)(c2ccccc2)S(=O)(=O)C(Cl)(c2ccccc2)c2ccc(C)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 9/20 0.44
CA9 Q16790 3/20 0.42
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA5A P35218 1/20 0.41
TSHR P16473 3/20 0.39
C5AR1 P21730 1/20 0.39
AGER Q15109 1/20 0.39
LMNA P02545 2/20 0.39
ALOX12 P18054 1/20 0.39
ACHE P22303 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
HTT P42858 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7112101 0.77 TSHR (0.37) KIF11CA9CA1CA2CA5A
SCHEMBL7644095 0.76 TSHR (0.48) KIF11TSHRLMNAALOX12ACHE
SCHEMBL118809 0.76 TSHR (0.48) KIF11TSHRLMNAALOX12ACHE
SCHEMBL2484318 0.76 TSHR (0.48) KIF11TSHRLMNAALOX12ACHE
SCHEMBL11590726 0.76 MEN1 (0.44) KIF11CA9CA12CA1CA2
SCHEMBL3896633 0.75 CA12 (0.40) KIF11CA9CA12CA1CA2
SCHEMBL16933918 0.74 TSHR (0.50) KIF11TSHRLMNAALOX12ACHE
P-Xylene SCHEMBL29242628 0.73 TSHR (0.74) KIF11TSHRLMNAALOX12ACHE
SCHEMBL11961957 0.73 CA9 (0.47) KIF11CA9CA12CA1CA2
SCHEMBL28278170 0.72 MEN1 (0.47) KIF11TSHRLMNAALOX12ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed