Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118809 | 1.00 | TSHR (0.48) | TSHRACHELMNAALOX12KIF11 | |
| Chlorotriphenylmethane SCHEMBL29248291 | 0.92 | TSHR (0.58) | TSHRACHELMNAALOX12KIF11 | |
| SCHEMBL11527250 | 0.89 | TSHR (0.55) | TSHRACHELMNAALOX12HPGD | |
| SCHEMBL11588689 | 0.89 | TSHR (0.55) | TSHRACHELMNAALOX12HPGD | |
| SCHEMBL12379580 | 0.88 | KIF11 (0.44) | TSHRACHELMNAALOX12KIF11 | |
| SCHEMBL13379252 | 0.88 | KIF11 (0.40) | TSHRACHELMNAALOX12KIF11 | |
| SCHEMBL16321127 | 0.86 | ACHE (0.56) | TSHRACHELMNAKIF11SMN1; SMN2 | |
| SCHEMBL17753724 | 0.86 | KIF11 (0.47) | TSHRLMNAKIF11MEN1KMT2A | |
| SCHEMBL12730666 | 0.86 | ACHE (0.56) | TSHRACHELMNAKIF11SMN1; SMN2 | |
| SCHEMBL7644095 | 0.85 | TSHR (0.48) | TSHRACHELMNAALOX12KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677810-A | Double-stranded oligonucleotide, composition containing double-stranded oligonucleotide, conjugate, preparation method and application | 苏州瑞博生物技术股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-1970445-B1 | METHOD FOR NUCLEIC ACID REPLICATION AND NOVEL ARTIFICIAL BASE PAIRS | RIKEN (JP) | 2012-09-26 | — | — | EP | disclosed |
| US-8207093-B2 | Producing libraries; including high salt post translational incubation step | THE GENERAL HOSPITAL CORPORATION (US) | 2012-06-26 | — | — | US | disclosed |
| EP-1712623-B1 | Selection of proteins using RNA-protein fusions | GEN HOSPITAL CORP (US) | 2011-10-19 | — | — | EP | disclosed |
| US-8030478-B2 | Method for nucleic acid replication and novel artificial base pairs | RIKEN (JP) | 2011-10-04 | — | — | US | disclosed |
| US-7705222-B2 | methods, compositions and apparatus for detection, identification and/or sequencing of nucleic acids and/or other biomolecules using nano-barcodes and scanning probe microscopy; high speed of obtaining sequence data, low cost of sequencing, high efficiency in terms of amount of operator time required | INTEL CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100036111-A1 | METHOD FOR REPLICATING NUCLEIC ACIDS AND NOVEL UNNATURAL BASE PAIRS | RIKEN (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-1151143-B1 | SELECTION OF PROTEINS USING RNA-PROTEIN FUSIONS | GEN HOSPITAL CORP (US) | 2009-04-08 | — | — | EP | disclosed |
| US-7476786-B2 | Using nanoparticles to identify and/or sequence biomolecules; forensic analysis; medical diagnostics | INTEL CORPORATION (US) | 2009-01-13 | — | — | US | disclosed |
| EP-1970445-A1 | METHOD FOR NUCLEIC ACID REPLICATION AND NOVEL ARTIFICIAL BASE PAIRS | Riken (JP) | 2008-09-17 | — | — | EP | disclosed |
| WO-2001002415-A1 | C3'-METHYLENE HYDROGEN PHOSPHONATE MONOMERS AND RELATED COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2001002419-A1 | C3'-METHYLENE HYDROGEN PHOSPHONATE OLIGOMERS AND RELATED COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2000047775-A1 | SELECTION OF PROTEINS USING RNA-PROTEIN FUSIONS | THE GENERAL HOSPITAL CORPORATION (US) | 2000-08-17 | — | — | WO | disclosed |
| CN-1251593-A | Selection of proteins using RNA-protein fusions | GEN HOSPITAL CORP (US) | 2000-04-26 | — | — | CN | disclosed |
| EP-0971946-A1 | SELECTION OF PROTEINS USING RNA-PROTEIN FUSIONS | THE GENERAL HOSPITAL CORPORATION (US) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998031700-A1 | SELECTION OF PROTEINS USING RNA-PROTEIN FUSIONS | THE GENERAL HOSPITAL CORPORATION (US) | 1998-07-23 | — | — | WO | disclosed |
| EP-0691979-A1 | NOVEL 5'-SUBSTITUTED NUCLEOSIDES AND OLIGOMERS PRODUCED THEREFROM | SANOFI (FR) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994022890-A1 | NOVEL 5'-SUBSTITUTED NUCLEOSIDES AND OLIGOMERS PRODUCED THEREFROM | STERLING WINTHOP INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| EP-0083777-A1 | Physiologically active peptide with between 147 and 162 amino acid residues | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-07-20 | — | — | EP | disclosed |
| US-4098894-A | FUNGICIDES AND BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036111-A1 | METHOD FOR REPLICATING NUCLEIC ACIDS AND NOVEL UNNATURAL BASE PAIRS | POLM, POLL, POLRMT | TSHR 3466/4885ACHE 4828/4885LMNA 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.