Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7112122 | 1.00 | TDP1 (0.59) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL6881757 | 1.00 | TDP1 (0.59) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL6881761 | 1.00 | TDP1 (0.59) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL23387512 | 0.98 | TDP1 (0.57) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL14514188 | 0.93 | TDP1 (0.67) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL10886972 | 0.93 | TDP1 (0.67) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL11391935 | 0.93 | TDP1 (0.67) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL11391960 | 0.93 | TDP1 (0.67) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL3171676 | 0.85 | LMNA (0.65) | TDP1LMNATSHRALDH1A1NT5E | |
| SCHEMBL29990536 | 0.85 | LMNA (0.65) | TDP1LMNATSHRALDH1A1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968255-B1 | PIGMENT FLAKES | MERCK PATENT GMBH (DE) | 2003-05-28 | — | — | EP | disclosed |
| US-6552102-B2 | Pigment flakes comprise at least one dye that is chemically bound to the polymer | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2003-04-22 | — | — | US | disclosed |
| US-20030017280-A1 | Pigment flakes | POETSCH EIKE (DE) | 2003-01-23 | — | — | US | disclosed |
| EP-0968255-A1 | PIGMENT FLAKES | MERCK PATENT GmbH (DE) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998042799-A1 | PIGMENT FLAKES | MERCK PATENT GMBH (DE) | 1998-10-01 | — | — | WO | disclosed |