Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1942389 | 1.00 | MAPT (0.57) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL1942388 | 1.00 | MAPT (0.57) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5895201 | 0.90 | MAPT (0.55) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5895221 | 0.90 | MAPT (0.55) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5895214 | 0.90 | MAPT (0.55) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL10437636 | 0.89 | LMNA (0.60) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL27923701 | 0.87 | LMNA (0.53) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL5895978 | 0.87 | MAPT (0.56) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL9650073 | 0.87 | MAPT (0.53) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL8509303 | 0.87 | LMNA (0.64) | MAPTLMNAALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990318-A | Soluble polyester-supported chiral phosphines | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 1999-11-23 | — | — | US | claimed |
| EP-1041077-B1 | Phosphine derivative and polymer thereof and transition metal complex comprising the same | TAKASAGO PERFUMERY CO LTD (JP) | 2003-11-05 | — | — | EP | disclosed |
| EP-1041077-A2 | Phosphine derivative and polymer thereof and transition metal complex comprising the same | Takasago International Corporation (JP) | 2000-10-04 | — | — | EP | disclosed |
| US-5990318-A | Soluble polyester-supported chiral phosphines | THE HONG KONG POLYTECHNIC UNIVERSITY (HK) | 1999-11-23 | — | — | US | disclosed |
| US-4010181-A | BIS(PHOSPHINOMETHYL)CYCLOBUTANE RHODIUM COMPLEXES | RHONE-POULENC S.A. (FR) | 1977-03-01 | — | — | US | disclosed |
| US-3978101-A | HYDROGENATION CATALYSTS | RHONE-POULENC S.A. (FR) | 1976-08-31 | — | — | US | disclosed |
| US-3949000-A | COMPLEX FORMERS | RHONE-POULENC S.A. (FR) | 1976-04-06 | — | — | US | disclosed |