Urethane

Urethane

SCHEMBL7112256

CCOC(N)=O.NC(=O)NN=C=O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 1/20 0.35
MAPT P10636 1/20 0.34
CAD P27708 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 3/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
SOAT1 P35610 1/20 0.31
MAPK1 P28482 1/20 0.31
CHRM2 P08172 1/20 0.31
CHRM4 P08173 1/20 0.31
HTR1A P08908 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515134 0.79
Urethane SCHEMBL4443807 0.78 ALOX15 (0.68) ALOX15MGAMGAASIMGAM2
Urethane SCHEMBL6233111 0.77
Urethane SCHEMBL11589533 0.77
SCHEMBL472886 0.76
Urethane SCHEMBL10632237 0.76 ALOX15 (0.65) ALOX15MGAMGAASIMGAM2
Urethane SCHEMBL7922234 0.76 ALOX15 (0.65) ALOX15MGAMGAASIMGAM2
Urethane SCHEMBL11766739 0.75 ALOX15 (0.79) ALOX15MGAMGAASIMGAM2
Urethane SCHEMBL10338136 0.75 ALOX15 (0.62) ALOX15MGAMGAASIMGAM2
Urethane SCHEMBL367439 0.74 ALOX15 (1.00) ALOX15MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0816445-B1 Isocyanate-derived materials for use in phase change ink jet inks XEROX CORP (US) 2003-05-02 EP claimed
CN-101319098-B Quinacridone nanoscale pigment particles XEROX CORP 2013-05-22 CN disclosed
CN-101319098-A Quinacridone nanoscale pigment particles XEROX CORP (US) 2008-12-10 CN disclosed
CN-101319097-A Nanosized particles of monoazo laked pigment XEROX CORP (US) 2008-12-10 CN disclosed
EP-0816446-B1 Phase change ink formulation using a urethane and urethane urea isocyanate derived resins XEROX CORP (US) 2003-09-03 EP disclosed
US-5830942-A Phase change ink formulation using a urethane and urethane/urea isocyanate-derived resins TEKTRONIX, INC. (US) 1998-11-03 US disclosed
EP-0816446-A1 Phase change ink formulation using a urethane and urethane urea isocyanate derived resins TEKTRONIX, INC. (US) 1998-01-07 EP disclosed