Fluoride Ion

Fluoride Ion

SCHEMBL7112279

[F-].[F-].c1c[nH]c([Ti+2]c2ccc[nH]2)c1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
AURKA O14965 1/20 0.33
AURKB Q96GD4 1/20 0.33
INCENP Q9NQS7 1/20 0.33
FKBP5 Q13451 1/20 0.32
MCL1 Q07820 1/20 0.30
NAPRT Q6XQN6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7113983 0.94 DAO (0.33) DAOHDAC8HDAC6AURKAAURKB
Bromide SCHEMBL7114917 0.94 DAO (0.33) DAOHDAC8HDAC6AURKAAURKB
Hydrochloric Acid SCHEMBL8460076 0.69
Hydrochloric Acid SCHEMBL8459559 0.69
Hydrochloric Acid SCHEMBL8462899 0.67
SCHEMBL544524 0.61 DAO (0.35) DAOHDAC8HDAC6AURKAAURKB
Fluoride Ion SCHEMBL14954141 0.61
Fluoride Ion SCHEMBL14954299 0.61
Fluoride Ion SCHEMBL14954329 0.61
SCHEMBL630634 0.60 HDAC6 (0.41) DAOHDAC8HDAC6AURKAAURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0834514-B1 Process for synthesizing metallocene compounds KANTO KAGAKU (JP) 2003-10-22 EP disclosed
US-5892075-A Process for synthesizing metallocene compounds KANTO KAGAKU KABUSHIKI KAISHA (JP) 1999-04-06 US disclosed
EP-0834514-A2 Process for synthesizing metallocene compounds KANTO KAGAKU KABUSHIKI KAISHA (JP) 1998-04-08 EP disclosed