Picloram

Picloram

SCHEMBL7112378

Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.[S-2].[S-2].[S-2].[S-2].[S-2]

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.96
MAPT P10636 3/20 0.47
LMNA P02545 3/20 0.47
GAA P10253 3/20 0.47
ATM Q13315 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
NOX1 Q9Y5S8 1/20 0.38
KMO O15229 1/20 0.35
HCAR2 Q8TDS4 1/20 0.34
ALDH1A1 P00352 4/20 0.34
KDM4E B2RXH2 3/20 0.34
GLA P06280 3/20 0.34
HPGD P15428 3/20 0.34
HSD17B10 Q99714 3/20 0.34
PLAU P00749 2/20 0.34
CYP1A2 P05177 2/20 0.34
SLC9A1 P19634 2/20 0.34
SLC22A1 O15245 1/20 0.34
HTR1A P08908 1/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Picloram SCHEMBL13299 0.98 TDP1 (1.00) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL29388079 0.98 TDP1 (1.00) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL8467014 0.98 TDP1 (1.00) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL29705200 0.96 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL18112562 0.96 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL5086801 0.96 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL724603 0.96 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL28547325 0.96 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL15437675 0.96 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL4936972 0.92 TDP1 (0.89) TDP1MAPTLMNAGAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0622444-B2 USE OF INORGANIC PHOSPHORUS COMPOUNDS AS FRICTION IMPROVERS IN WET CLUTCH OR WET BRAKE LUBRICANT COMPOSITIONS ETHYL JAPAN CORP (JP) 2003-10-22 EP disclosed
EP-0622444-B1 USE OF INORGANIC PHOSPHORUS COMPOUNDS AS FRICTION IMPROVERS IN WET CLUTCH OR WET BRAKE LUBRICANT COMPOSITIONS ETHYL JAPAN CORP (JP) 1999-12-29 EP disclosed
EP-0286996-B2 Lubricating oil composition IDEMITSU KOSAN CO (JP) 1999-12-08 EP disclosed
EP-0630960-B1 Lubricating oil composition IDEMITSU KOSAN CO (JP) 1999-08-25 EP disclosed
US-5851962-A Lubricant composition for wet clutch or wet brake ETHYL JAPAN CORPORATION (JP) 1998-12-22 US disclosed
US-5516440-A OXIDATION RESISTANCE FOR OILS FOR TRANSMISSION IDEMITSU KOSAN CO., LTD. (JP) 1996-05-14 US disclosed
EP-0630960-A1 Lubricating oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1994-12-28 EP disclosed
EP-0622444-A1 LUBRICATING OIL COMPOSITION FOR WET CLUTCH OR WET BRAKE ETHYL JAPAN CORPORATION (JP) 1994-11-02 EP disclosed
US-5273672-A Lubricating oil composition containing a partial ester of a polyhydric alcohol and a substituted succinic acid ester IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-12-28 US disclosed
EP-0305538-B1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-12-23 EP disclosed
EP-0259809-B1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-04-29 EP disclosed
EP-0259808-B1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-04-22 EP disclosed
US-5064546-A Friction modifier IDEMITSU KOSAN CO., LTD. (JP) 1991-11-12 US disclosed
US-4968452-A TRANSMISSION FLUIDS, HYDRAULIC FLUIDS, ENGINE OILS IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-11-06 US disclosed
US-4960542-A Friction resistance; oxidation resistance; rubber compatibility IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-10-02 US disclosed
EP-0305538-A1 LUBRICATING OIL COMPOSITION IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-03-08 EP disclosed
EP-0286996-A2 Lubricating oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-10-19 EP disclosed
EP-0259808-A2 Lubricating oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-03-16 EP disclosed
EP-0259809-A2 Lubricating oil composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-03-16 EP disclosed