Picloram

Picloram

SCHEMBL8467014

Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl.Nc1c(Cl)c(Cl)nc(C(=O)O)c1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 1.00
MAPT P10636 3/20 0.49
LMNA P02545 3/20 0.49
GAA P10253 3/20 0.49
ATM Q13315 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
NOX1 Q9Y5S8 1/20 0.39
KMO O15229 1/20 0.36
HCAR2 Q8TDS4 1/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
GLA P06280 3/20 0.35
HPGD P15428 3/20 0.35
HSD17B10 Q99714 3/20 0.35
PLAU P00749 2/20 0.35
CYP1A2 P05177 2/20 0.35
SLC9A1 P19634 2/20 0.35
SLC22A1 O15245 1/20 0.35
HTR1A P08908 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Picloram SCHEMBL29388079 1.00 TDP1 (1.00) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL13299 1.00 TDP1 (1.00) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL7112378 0.98 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL28547325 0.98 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL18112562 0.98 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL5086801 0.98 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL724603 0.98 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL29705200 0.98 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL15437675 0.98 TDP1 (0.96) TDP1MAPTLMNAGAAATM
Picloram SCHEMBL4936972 0.94 TDP1 (0.89) TDP1MAPTLMNAGAAATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880328-A ANTI-PATHOGENIC SEQUENCES DERIVED FROM NOVEL CDNAS CODING FOR PR PROTEINS WHICH CAN BE GENETICALLY ENGINEERED AND TRANSFORMED INTO PLANTS TO CONFER ENHANCED RESISTANCE TO DISEASE NOVARTIS FINANCE CORPORATION (US) 1999-03-09 US disclosed
US-5856154-A DNA SEQUENCES NOVARTIS FINANCE CORPORATION (US) 1999-01-05 US disclosed
EP-0574418-B1 ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1998-11-11 EP disclosed
US-5789214-A TRANSPORTATION OF PLANT TISSUES, NUCLEIC ACID PROMOTER FRAGMENTS, CODES AND EXPOSING TISSUES NOVARTIS FINANCE CORPORATION (US) 1998-08-04 US disclosed
US-5689044-A GENETIC ENGINEERING NOVARTIS CORPORATION (US) 1997-11-18 US disclosed
US-5688745-A Arylsulfonylureas and their use as herbicides and growth regulators HOECHST AKTIENGESELLSCHAFT (DE) 1997-11-18 US disclosed
US-RE35661-E LETTUCE IDAHO RESEARCH FOUNDATION, INC. (US) 1997-11-11 US disclosed
US-5654414-A GENETIC ENGINEERING NOVARTIS FINANCE CORPORATION (US) 1997-08-05 US disclosed
US-5614395-A SCREENING FOR AGROCHEMICALS HAVING THE ABILITY TO INDUCE SYSTEMIC ACQUIRED RESISTANCE IN PLANTS CIBA-GEIGY CORPORATION (US) 1997-03-25 US disclosed
EP-0575503-A1 HERBICIDAL PYRIDINE SULFONAMIDE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-29 EP disclosed
WO-1991010653-A1 HERBICIDAL PYRIMIDINES AND TRIAZINES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-25 WO disclosed
WO-1991003464-A1 HERBICIDAL OXABICYCLO ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-21 WO disclosed
EP-0394324-A1 HERBICIDAL o-CARBOMETHOXYSULFONYLUREA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-31 EP disclosed
WO-1990012012-A1 SUBSTITUTED PHENYLTRIAZOLOPYRIMIDINE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-18 WO disclosed
EP-0392225-A2 Disease-resistant transgenic plants CIBA-GEIGY AG (CH) 1990-10-17 EP disclosed
WO-1990010634-A1 SELECTIVE OXABICYCLOALKANES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-20 WO disclosed
WO-1990009383-A1 HERBICIDAL OXABICYCLONONANE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-23 WO disclosed
WO-1990002130-A2 HERBICIDES FOR WEED CONTROL IN SUGAR BEETS, OILSEED RAPE AND COLE CROPS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-08 WO disclosed
WO-1989004606-A1 HERBICIDAL o-CARBOMETHOXYSULFONYLUREA E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-06-01 WO disclosed
EP-0019796-A1 Propionic acid esters, preparation of these compounds, herbicides containing these compounds as active substances, and the use of such compounds and agents for combating weeds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-12-10 EP disclosed