Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659411 | 0.81 | L3MBTL1 (0.46) | TDP1L3MBTL1CHRM4CHRM3MEN1 | |
| SCHEMBL11058318 | 0.80 | ATM (0.41) | ATMTDP1L3MBTL1CHRM4CHRM3 | |
| SCHEMBL9728263 | 0.80 | HCAR2 (0.51) | ATMTDP1L3MBTL1CHRM4CHRM3 | |
| SCHEMBL16965403 | 0.74 | ATM (0.55) | ATMTDP1L3MBTL1CHRM4CHRM3 | |
| SCHEMBL16964940 | 0.72 | L3MBTL1 (0.52) | ATMTDP1L3MBTL1CHRM4CHRM3 | |
| SCHEMBL7106164 | 0.71 | L3MBTL1 (0.41) | ATMTDP1L3MBTL1CHRM4CHRM3 | |
| Trolamine SCHEMBL11286441 | 0.70 | HCAR2 (0.42) | ATMTDP1L3MBTL1CHRM4CHRM3 | |
| SCHEMBL16965722 | 0.70 | ATM (0.50) | ATMTDP1L3MBTL1CHRM4CHRM3 | |
| SCHEMBL16965086 | 0.68 | ATM (0.47) | ATMTDP1L3MBTL1CHRM4CHRM3 | |
| SCHEMBL16964924 | 0.68 | ATM (0.47) | ATMTDP1L3MBTL1CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013639-B1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | HOFFMANN LA ROCHE (CH) | 2003-10-01 | — | — | EP | disclosed |
| EP-1013639-A1 | Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit | F. HOFFMANN-LA ROCHE AG (CH) | 2000-06-28 | — | — | EP | disclosed |