SCHEMBL7112408

SCHEMBL7112408

CC1=NN(c2c(F)c(F)c(F)c(F)c2F)C(=O)C1.CC1=NN(c2ccccc2C(F)(F)F)C(=O)C1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.47
ALDH1A1 P00352 7/20 0.47
KMT2A Q03164 7/20 0.47
TDP1 Q9NUW8 5/20 0.47
MEN1 O00255 5/20 0.47
KDM4E B2RXH2 4/20 0.47
GAA P10253 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP1A2 P05177 1/20 0.47
CHRM2 P08172 1/20 0.47
CYP3A4 P08684 1/20 0.47
CHRM1 P11229 1/20 0.47
TSHR P16473 1/20 0.47
PTGS1 P23219 1/20 0.47
DRD3 P35462 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.44
APAF1 O14727 1/20 0.44
APP P05067 7/20 0.43
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133533 0.91 MAPT (0.55) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL1110348 0.79 MAPT (0.50) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL15364015 0.78 MAPT (0.50) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL3533968 0.75 KMT2A (0.60) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL3535015 0.75 LOX (0.60) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL4339175 0.73 MAPT (0.47) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL3534371 0.72 ALDH1A1 (0.39) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL4664740 0.72 MAPT (0.64) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL3529246 0.71 ALDH1A1 (0.40) MAPTALDH1A1KMT2ATDP1MEN1
SCHEMBL15364017 0.71 MAPT (0.51) MAPTALDH1A1KMT2ATDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1293835-A2 Electrophotographic toner with stable triboelectric properties Heidelberger Druckmaschinen Aktiengesellschaft (DE) 2003-03-19 EP claimed