SCHEMBL7112502

SCHEMBL7112502

CCCCCCCCCCCCCCCCOc1cc(N)c(O)cc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.51
SMPD1 P17405 1/20 0.43
THRA P10827 2/20 0.42
THRB P10828 2/20 0.42
MCHR1 Q99705 1/20 0.41
TLR8 Q9NR97 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NR5A1 Q13285 1/20 0.41
MEN1 O00255 1/20 0.41
NR1I2 O75469 1/20 0.41
LMNA P02545 1/20 0.41
CHRM2 P08172 1/20 0.41
CYP3A4 P08684 1/20 0.41
ADRA2A P08913 1/20 0.41
MAPT P10636 1/20 0.41
OPRK1 P41145 1/20 0.41
HTR2B P41595 1/20 0.41
SLC6A3 Q01959 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11053746 0.98 ESR1 (0.50) ESR1SMPD1THRATHRBMCHR1
SCHEMBL14015793 0.85 ESR1 (0.58) ESR1SMPD1THRATHRBNR5A1
SCHEMBL27224315 0.81 ESR1 (0.44) ESR1THRATHRBMCHR1TLR8
SCHEMBL4429554 0.81 ESR1 (0.44) ESR1THRATHRBMCHR1TLR8
SCHEMBL7781059 0.81 ESR1 (0.48) ESR1TSHR
SCHEMBL11230722 0.81 ESR1 (0.42) ESR1THRATHRBMCHR1TLR8
SCHEMBL13475563 0.80 ESR1 (0.51) ESR1THRATHRBMCHR1TLR8
SCHEMBL15200209 0.80 ESR1 (0.51) ESR1THRATHRBMCHR1TLR8
SCHEMBL862599 0.80 ESR1 (0.51) ESR1THRATHRBMCHR1TLR8
SCHEMBL13475571 0.80 ESR1 (0.51) ESR1THRATHRBMCHR1TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1353222-A1 Photographic element containing azole couplers EASTMAN KODAK COMPANY (US) 2003-10-15 EP disclosed
US-6521397-B1 Support bearing light sensitive silver halide emulsion layer having associated such as 2-benzoazoacetoitrile derivative dye forming coupler; improved absorption maximum and color gamut EASTMAN KODAK COMPANY 2003-02-18 US disclosed
US-4233237-A CHEMICAL INTERMEDIATE OF A DYE RELEASING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-11-11 US disclosed
US-4055428-A COLO PHOTOGRAPHY, DIFFUSION TRANSFER SILVER HALIDE EMULSIONS FUJI PHOTO FILM CO., LTD. (JA) 1977-10-25 US disclosed