Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835648 | 0.97 | KDM4E (0.50) | KDM4ELMNAHTTATMALDH1A1 | |
| SCHEMBL18380643 | 0.91 | KDM4E (0.61) | KDM4ELMNAHTTATMALDH1A1 | |
| SCHEMBL371 | 0.89 | KDM4E (0.49) | KDM4ELMNAHTTATMALDH1A1 | |
| SCHEMBL11491135 | 0.87 | KDM4E (0.47) | KDM4ELMNAHTTATMALDH1A1 | |
| SCHEMBL8873328 | 0.85 | RARB (0.50) | KDM4ELMNAHTTMAPTIL2 | |
| SCHEMBL342910 | 0.85 | KDM4E (0.59) | KDM4ELMNAHTTATMALDH1A1 | |
| SCHEMBL11485826 | 0.85 | KDM4E (0.45) | KDM4ELMNAHTTATMALDH1A1 | |
| SCHEMBL9256007 | 0.85 | KDM4E (0.45) | KDM4ELMNAHTTATMALDH1A1 | |
| SCHEMBL7004170 | 0.85 | KDM4E (0.45) | KDM4ELMNAHTTATMALDH1A1 | |
| SCHEMBL7934334 | 0.85 | KDM4E (0.45) | KDM4ELMNAHTTATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169289-B1 | METHOD FOR PRODUCING DERIVATIVES OF BIPHENYL-2-CARBOXYLIC ACID | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-10-29 | — | — | EP | disclosed |
| US-6369271-B1 | SAPONIFICATION WITH HYDROCHLORIC ACID, HEATING WITH PRESSURIZATION | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-04-09 | — | — | US | disclosed |
| EP-1169289-A1 | METHOD FOR PRODUCING DERIVATIVES OF BIPHENYL-2-CARBOXYLIC ACID | Boehringer Ingelheim Pharma KG (DE) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000051961-A1 | METHOD FOR PRODUCING DERIVATIVES OF BIPHENYL-2-CARBOXYLIC ACID | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-08 | — | — | WO | disclosed |
| US-4220778-A | ANTIARRHYTHMIC, ANTIMICROBIAL AND CENTRAL NERVOUS SYSTEM ACTIVITY | G. D. SEARLE & CO. (US) | 1980-09-02 | — | — | US | disclosed |