Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | IL2 | P60568 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485826 | 0.94 | KDM4E (0.45) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL7112634 | 0.85 | KDM4E (0.53) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL371 | 0.84 | KDM4E (0.49) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL10835648 | 0.82 | KDM4E (0.50) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL29186677 | 0.82 | KDM4E (0.44) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL7937331 | 0.81 | FABP4 (0.42) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL8560175 | 0.81 | HTT (0.41) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL9121996 | 0.80 | KDM4E (0.47) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL7490435 | 0.80 | KDM4E (0.47) | KDM4ELMNAHRH3IL2HTT | |
| SCHEMBL8486524 | 0.80 | KDM4E (0.46) | KDM4ELMNAHRH3IL2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194599-B1 | Process for preparing biaryl compounds | CATALYTICA, INC. | 2001-02-27 | — | — | US | disclosed |
| US-5922898-A | Process for preparing biaryl compounds | CATALYTICA PHARMACEUTICALS, INC. (US) | 1999-07-13 | — | — | US | disclosed |