Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 7/20 | 0.37 |
| ▸ | SRC | P12931 | 6/20 | 0.37 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | ABL1 | P00519 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | HCK | P08631 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822032 | 0.88 | IGF1R (0.52) | IGF1REGFRSRCKDRABL1 | |
| SCHEMBL5819727 | 0.82 | NTRK1 (0.44) | MAP4K3CCNT1CDK9EGFRSRC | |
| SCHEMBL5817387 | 0.80 | LCK (0.46) | MAP4K3CCNT1CDK9EGFRSRC | |
| SCHEMBL6247706 | 0.80 | SRC (0.44) | KDM4EMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL6245151 | 0.77 | EGFR (0.44) | IGF1RMAP4K3EGFRSRCKDR | |
| SCHEMBL5822805 | 0.77 | SRC (0.40) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5812688 | 0.77 | EGFR (0.44) | IGF1RMAP4K3EGFRSRCKDR | |
| SCHEMBL6248834 | 0.76 | SRC (0.43) | IGF1RMAP4K3EGFRSRCKDR | |
| SCHEMBL29987502 | 0.75 | EIF2AK3 (0.46) | KDM4EALDH1A1MAPTIGF1RMAP4K3 | |
| SCHEMBL28881310 | 0.75 | EIF2AK3 (0.46) | KDM4EALDH1A1MAPTIGF1RMAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |