SCHEMBL711279

SCHEMBL711279

CC(C)C(O[SiH3])c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
TAAR1 Q96RJ0 3/20 0.40
AOC3 Q16853 2/20 0.38
ADRA2A P08913 1/20 0.37
ADRA2C P18825 1/20 0.37
CYP2D6 P10635 1/20 0.37
LMNA P02545 1/20 0.37
HIF1A Q16665 1/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
DPP4 P27487 2/20 0.35
F2 P00734 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1313965 0.86 THRB (0.39) THRBTAAR1AOC3ADRA2AADRA2C
SCHEMBL892810 0.80 THRB (0.44) THRBTAAR1AOC3ADRA2AADRA2C
SCHEMBL1157986 0.80 THRB (0.44) THRBTAAR1AOC3ADRA2AADRA2C
SCHEMBL9911361 0.78 THRB (0.57) THRBTAAR1AOC3ADRA2AADRA2C
SCHEMBL15113559 0.78 THRB (0.57) THRBTAAR1AOC3ADRA2AADRA2C
SCHEMBL12884228 0.78 THRB (0.57) THRBTAAR1AOC3ADRA2AADRA2C
SCHEMBL28437689 0.77 SLC6A4 (0.39) THRBADRA2AADRA2CLMNAKDM4E
SCHEMBL28437690 0.77 SLC6A4 (0.39) THRBADRA2AADRA2CLMNAKDM4E
SCHEMBL13641888 0.76 THRB (0.41) THRBTAAR1AOC3ADRA2AADRA2C
SCHEMBL7929659 0.76 THRB (0.41) THRBTAAR1AOC3ADRA2AADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0728362-B1 JACKET MATERIAL FOR PROTECTION OF ELECTRICAL CONDUCTORS GORE & ASS (US) 1999-08-25 EP claimed
CN-109641482-B Preparation of cis-1, 4-polydienes having multiple silane functional groups prepared by in situ hydrosilylation of polymer glues 株式会社普利司通 2021-11-05 CN disclosed
EP-3103805-B1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND AIST (JP) 2020-11-18 EP disclosed
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-04 US disclosed
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-06-29 US disclosed
EP-3103805-A1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND National Institute of Advanced Industrial Science and Technology (JP) 2016-12-14 EP disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound LSS, MSMO1, ALG3 THRB 4615/4885TAAR1 3288/4885AOC3 1419/4885
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound LSS, MSMO1, ALG3 THRB 4615/4885TAAR1 3288/4885AOC3 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.