SCHEMBL7112911

SCHEMBL7112911

CCOc1ccccc1C(O[SiH3])(OCC)OCC

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
L3MBTL1 Q9Y468 5/20 0.39
MAPT P10636 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
GRM5 P41594 1/20 0.36
GAA P10253 1/20 0.35
HCRTR1 O43613 1/20 0.35
HPGD P15428 3/20 0.34
HSD17B10 Q99714 1/20 0.34
ALOX15 P16050 1/20 0.34
KCNK3 O14649 1/20 0.34
KCNK9 Q9NPC2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31005286 0.89 ALDH1A1 (0.48) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL1069637 0.79 ALDH1A1 (0.46) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL28874713 0.75 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTNPSR1GLA
Hydrochloric Acid SCHEMBL29012586 0.74 ALDH1A1 (0.48) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL6763906 0.74 CYP1A2 (0.53) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL5921936 0.72 ALDH1A1 (0.43) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL474157 0.72 KCNN4 (0.38) ALDH1A1CYP2D6ALOX15
SCHEMBL6946500 0.72 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL31035275 0.72 ALDH1A1 (0.50) ALDH1A1L3MBTL1MAPTNPSR1GLA
SCHEMBL28399862 0.71 ALDH1A1 (0.48) ALDH1A1L3MBTL1MAPTNPSR1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3103805-B1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND AIST (JP) 2020-11-18 EP disclosed
CN-106632744-B Propylene polymerization catalyst, preparation method and application 北京化工大学 2020-05-15 CN disclosed
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-04 US disclosed
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-06-29 US disclosed
EP-3103805-A1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND National Institute of Advanced Industrial Science and Technology (JP) 2016-12-14 EP disclosed
EP-0754739-B1 Curable coating composition KANSAI PAINT CO LTD (JP) 2003-10-29 EP disclosed
US-5684095-A POLYESTER, POLYEPOXIDE, SILICON COMPOUND AND CHELATE CMPOUND IN SOLVENT KANSAI PAINT COMPANY, LIMITED (JP) 1997-11-04 US disclosed
EP-0754739-A2 Curable coating composition KANSAI PAINT CO., LTD. (JP) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound LSS, MSMO1, ALG3 ALDH1A1 1273/4885L3MBTL1 3847/4885MAPT 2334/4885
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound LSS, MSMO1, ALG3 ALDH1A1 1273/4885L3MBTL1 3847/4885MAPT 2334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.