Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL215052 | 0.89 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594051 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594665 | 0.82 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5604428 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8797587 | 0.80 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL5594720 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Sulfamide SCHEMBL4639044 | 0.79 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL5594264 | 0.79 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL5604642 | 0.77 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594456 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480637-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A BISPHOSPHONATE AND A COX-2 INHIBITOR FOR THE TREATMENT OF BONE DISEASES | Novartis AG (CH) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003072097-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A BISPHOSPHONATE AND A COX-2 INHIBITOR FOR THE TREATMENT OF BONE DISEASES | NOVARTIS AG (CH) | 2003-09-04 | — | — | WO | disclosed |