Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.94 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7114503 | 1.00 | CHRNA7 (0.94) | CHRNA7CHRM2CHRM1MEN1CYP2D6 | |
| Bromide SCHEMBL19834621 | 1.00 | CHRNA7 (0.94) | CHRNA7CHRM2CHRM1MEN1CYP2D6 | |
| SCHEMBL47241 | 0.97 | — | — | |
| SCHEMBL260640 | 0.97 | — | — | |
| SCHEMBL9431600 | 0.97 | — | — | |
| SCHEMBL17203543 | 0.97 | — | — | |
| SCHEMBL427062 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL492194 | 0.94 | CHRNA7 (0.94) | CHRNA7CHRM2CHRM1MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL2183739 | 0.94 | CHRNA7 (0.94) | CHRNA7CHRM2CHRM1MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL348634 | 0.94 | CHRNA7 (0.94) | CHRNA7CHRM2CHRM1MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945496-B1 | Ink compositions and multicolor thermal ink jet printing process for the production of high quality images | XEROX CORP (US) | 2003-11-12 | — | — | EP | claimed |
| EP-0945496-A1 | Ink compositions and multicolor thermal ink jet printing process for the production of high quality images | Xerox Corporation (US) | 1999-09-29 | — | — | EP | claimed |
| US-5958121-A | SET OF INKS COMPRISING FIRST AQUEOUS INK CONSISTING OF ANIONIC COLORANT, SECOND AQUEOUS INK CONTAINING AMMONIUM SALT, WHEREIN FIRST COLORANT IS IMMOBILIZED ON SUBSTRATE BY INTERACTION WITH AMMONIUM SALT, REDUCING INTERCOLOR BLEED | XEROX CORPORATION (US) | 1999-09-28 | — | — | US | claimed |
| EP-0945496-B1 | Ink compositions and multicolor thermal ink jet printing process for the production of high quality images | XEROX CORP (US) | 2003-11-12 | — | — | EP | disclosed |
| EP-0945496-A1 | Ink compositions and multicolor thermal ink jet printing process for the production of high quality images | Xerox Corporation (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5958121-A | SET OF INKS COMPRISING FIRST AQUEOUS INK CONSISTING OF ANIONIC COLORANT, SECOND AQUEOUS INK CONTAINING AMMONIUM SALT, WHEREIN FIRST COLORANT IS IMMOBILIZED ON SUBSTRATE BY INTERACTION WITH AMMONIUM SALT, REDUCING INTERCOLOR BLEED | XEROX CORPORATION (US) | 1999-09-28 | — | — | US | disclosed |