Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 1/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 9/20 | 0.48 |
| ▸ | MMP1 | P03956 | 4/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7114506 | 1.00 | BIRC2 (0.52) | BIRC2BMP1MMEECE1ANPEP | |
| SCHEMBL7118008 | 0.93 | BIRC2 (0.53) | BIRC2BMP1MMP2MMP1MMP3 | |
| SCHEMBL7084246 | 0.93 | BIRC2 (0.53) | BIRC2BMP1MMP2MMP1MMP3 | |
| SCHEMBL7118239 | 0.92 | BIRC2 (0.62) | BIRC2BMP1MMP2MMP1MMP3 | |
| SCHEMBL7118243 | 0.92 | BIRC2 (0.62) | BIRC2BMP1MMP2MMP1MMP3 | |
| SCHEMBL7084074 | 0.89 | BIRC2 (0.54) | BIRC2BMP1MMP2MMP1MMP3 | |
| SCHEMBL7077150 | 0.89 | BIRC2 (0.52) | BIRC2BMP1MMP2MMP1MMP3 | |
| SCHEMBL7077148 | 0.89 | BIRC2 (0.52) | BIRC2BMP1MMP2MMP1MMP3 | |
| SCHEMBL7787564 | 0.89 | MME (0.55) | BIRC2BMP1MMEMMP2MMP1 | |
| SCHEMBL7787562 | 0.89 | MME (0.55) | BIRC2BMP1MMEMMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476067-B1 | N-formyl hydroxylamine derivatives as antibacterial agents | BRITISH BIOTECH (GB) | 2002-11-05 | — | — | US | claimed |
| EP-1140058-B1 | N-FORMYL HYDROXYLAMINE DERIVATIVES AS ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARM (GB) | 2003-11-05 | — | — | EP | disclosed |
| US-6476067-B1 | N-formyl hydroxylamine derivatives as antibacterial agents | BRITISH BIOTECH (GB) | 2002-11-05 | — | — | US | disclosed |
| EP-1146868-A1 | ANTI-INFLAMMATORY AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-10-24 | — | — | EP | disclosed |
| EP-1140058-A1 | N-FORMYL HYDROXYLAMINE DERIVATIVES AS ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000043001-A1 | ANTI-INFLAMMATORY AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-07-27 | — | — | WO | disclosed |
| WO-2000035440-A1 | N-FORMYL HYDROXYLAMINE DERIVATIVES AS ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-06-22 | — | — | WO | disclosed |