Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | CPA1 | P15085 | 2/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.55 |
| ▸ | BMP1 | P13497 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 10/20 | 0.52 |
| ▸ | MMP1 | P03956 | 5/20 | 0.52 |
| ▸ | MMP3 | P08254 | 5/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787562 | 1.00 | MME (0.55) | MMEACECPA1ACE2BMP1 | |
| SCHEMBL7118239 | 0.90 | BIRC2 (0.62) | BMP1MMP2MMP1MMP3BIRC2 | |
| SCHEMBL7118243 | 0.90 | BIRC2 (0.62) | BMP1MMP2MMP1MMP3BIRC2 | |
| SCHEMBL14282135 | 0.90 | BMP1 (0.52) | BMP1MMP2MMP1MMP3HDAC3 | |
| SCHEMBL7118008 | 0.89 | BIRC2 (0.53) | BMP1MMP2MMP1MMP3HDAC3 | |
| SCHEMBL7084246 | 0.89 | BIRC2 (0.53) | BMP1MMP2MMP1MMP3HDAC3 | |
| SCHEMBL7114508 | 0.89 | BIRC2 (0.52) | MMEBMP1MMP2MMP1MMP3 | |
| SCHEMBL7114506 | 0.89 | BIRC2 (0.52) | MMEBMP1MMP2MMP1MMP3 | |
| SCHEMBL7084074 | 0.88 | BIRC2 (0.54) | BMP1MMP2MMP1MMP3MMP7 | |
| SCHEMBL7077148 | 0.88 | BIRC2 (0.52) | BMP1MMP2MMP1MMP3BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323448-B2 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |
| US-7323448-B2 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |
| EP-1146868-A1 | ANTI-INFLAMMATORY AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000043001-A1 | ANTI-INFLAMMATORY AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2000-07-27 | — | — | WO | disclosed |