Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.72 |
| ▸ | F2 | P00734 | 6/20 | 0.72 |
| ▸ | PLG | P00747 | 4/20 | 0.67 |
| ▸ | PROC | P04070 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124638 | 0.90 | F10 (1.00) | F10PRSS1F2PLGPROC | |
| SCHEMBL7123864 | 0.88 | F10 (0.84) | F10PRSS1F2PLGPROC | |
| SCHEMBL7121228 | 0.88 | F10 (0.84) | F10PRSS1F2PLGPROC | |
| SCHEMBL7117113 | 0.88 | F10 (1.00) | F10PRSS1F2PLGPROC | |
| SCHEMBL7117290 | 0.88 | F10 (0.78) | F10PRSS1F2PLGPROC | |
| SCHEMBL7124552 | 0.86 | F10 (0.75) | F10PRSS1F2PLGPROC | |
| SCHEMBL7124683 | 0.86 | F10 (0.75) | F10PRSS1F2PLGPROC | |
| SCHEMBL7123228 | 0.85 | F10 (0.80) | F10PRSS1F2PLGPROC | |
| SCHEMBL7126588 | 0.85 | F10 (0.91) | F10PRSS1F2PLGPROC | |
| SCHEMBL7123273 | 0.85 | F10 (0.91) | F10PRSS1F2PLGPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030187256-A1 | Benoxazinones/benzothiazinones as serine protease inhibitors | BERRYMAN KENT ALAN (US) | 2003-10-02 | — | — | US | disclosed |
| US-6509335-B1 | This invention discloses benzoxazinone and benzothiazinone compounds which display inhibitory effects on serine proteases such as factor Xa, thrombin, and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts of | WARNER-LAMBERT COMPANY | 2003-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187256-A1 | Benoxazinones/benzothiazinones as serine protease inhibitors | HABP2, SPINT2, SERPINB1 | F10 24/4885PRSS1 8/4885F2 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.