⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551299 | 0.87 | CYP2C19 (0.60) | — | |
| SCHEMBL19545977 | 0.83 | — | — | |
| SCHEMBL7262069 | 0.79 | CYP2C19 (0.52) | — | |
| Ethylene Glycol SCHEMBL2776457 | 0.79 | CYP2C19 (0.52) | — | |
| SCHEMBL21864588 | 0.77 | — | — | |
| SCHEMBL7908937 | 0.75 | CYP2C19 (0.55) | — | |
| SCHEMBL13637492 | 0.74 | CYP2C19 (0.39) | — | |
| SCHEMBL7180847 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL1532586 | 0.73 | — | — | |
| SCHEMBL6871500 | 0.73 | CYP2C19 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7994152-B2 | Method of treating a cancer by administering A 2′,5′-oligoadenylate analog | SANKYO COMPANY, LIMITED (JP) | 2011-08-09 | — | — | US | disclosed |
| US-7994152-B2 | Method of treating a cancer by administering A 2′,5′-oligoadenylate analog | SANKYO COMPANY, LIMITED (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20100035976-A1 | Method of treating a tumor or a viral disease by administering a 2' , 5' -oligoadenylate analog | SANKYO COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20100035976-A1 | Method of treating a tumor or a viral disease by administering a 2' , 5' -oligoadenylate analog | SANKYO COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-7651999-B2 | phosphorothioate modification containg oligonadenylates useful as antiviral, anticarcinogenic and antitumor agent; stable and have superior activity for treating lung cancer | SANKYO COMPANY, LIMITED (JP) | 2010-01-26 | — | — | US | disclosed |
| US-7651999-B2 | phosphorothioate modification containg oligonadenylates useful as antiviral, anticarcinogenic and antitumor agent; stable and have superior activity for treating lung cancer | SANKYO COMPANY, LIMITED (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20080146759-A1 | Sulfur-Containing Compound, Method for Producing Same, Sulfur-Containing Polymer, and Optical Material | IDEMITSU KOSAN CO., LTD (JP) | 2008-06-19 | — | — | US | disclosed |
| US-20030220524-A1 | Sulfur containing compounds | LANGLER RICHARD FRANCIS (CA) | 2003-11-27 | — | — | US | disclosed |
| EP-1259482-A2 | SULFUR CONTAINING COMPOUNDS | University Health Network (CA) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001062668-A2 | SULFUR CONTAINING COMPOUNDS | UNIVERSITY HEALTH NETWORK (CA) | 2001-08-30 | — | — | WO | disclosed |
| EP-0130025-B1 | 2-ALKYLTHIOPENEM DERIVATIVES | PFIZER INC. (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4619924-A | BACTERICIDES | PFIZER INC. (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0130025-A1 | 2-Alkylthiopenem derivatives | PFIZER INC. (US) | 1985-01-02 | — | — | EP | disclosed |