Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.43 |
| ▸ | MMP3 | P08254 | 8/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116166 | 0.91 | MMP2 (0.49) | MMP2MMP3MMP9MMP13MMP14 | |
| SCHEMBL7116153 | 0.91 | MMP2 (0.49) | MMP2MMP3MMP9MMP13MMP14 | |
| SCHEMBL7116162 | 0.83 | MMP2 (0.42) | MMP2MMP3MMP9MMP13MMP14 | |
| SCHEMBL7108965 | 0.83 | MMP2 (0.55) | MMP2MMP3MMP9MMP13MMP14 | |
| SCHEMBL7109196 | 0.78 | MMP2 (0.51) | MMP2MMP3 | |
| SCHEMBL7110227 | 0.75 | MMP2 (0.55) | MMP2MMP3MMP9MMP13MMP14 | |
| SCHEMBL7108961 | 0.74 | MMP2 (0.58) | MMP2MMP3MMP9MMP13MMP14 | |
| SCHEMBL7113031 | 0.71 | MMP2 (0.59) | MMP2MMP3MMP9MMP13MMP14 | |
| SCHEMBL7113038 | 0.71 | MMP2 (0.59) | MMP2MMP3MMP9MMP13MMP14 | |
| SCHEMBL7110231 | 0.68 | MMP2 (0.59) | MMP2MMP3MMP9MMP13MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047665-B1 | MATRIX METALLOPROTEASE INHIBITORS | PFIZER LTD (GB) | 2003-10-22 | — | — | EP | disclosed |
| US-6350907-B1 | PEPTIDE ENZYME INHIBITORS | PFIZER INC | 2002-02-26 | — | — | US | disclosed |