Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 12/20 | 0.52 |
| ▸ | MASP2 | O00187 | 3/20 | 0.52 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F13A1 | P00488 | 1/20 | 0.41 |
| ▸ | ESRRB | O95718 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7539002 | 0.99 | ST14 (0.54) | ST14F2MASP2PROCPRSS1 | |
| Hydrochloric Acid SCHEMBL6365937 | 0.91 | F2 (0.61) | ST14F2MASP2PROCPRSS1 | |
| SCHEMBL7428892 | 0.86 | ST14 (0.54) | ST14F2MASP2PROCPRSS1 | |
| Hydrochloric Acid SCHEMBL6365976 | 0.85 | ST14 (0.53) | ST14F2MASP2PROCPRSS1 | |
| Hydrochloric Acid SCHEMBL6365882 | 0.81 | F2 (0.48) | ST14F2MASP2PROC | |
| Hydrochloric Acid SCHEMBL6372032 | 0.81 | ST14 (0.61) | ST14F2PRSS1ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6366431 | 0.80 | ST14 (0.49) | ST14F2MASP2PROCPRSS1 | |
| Hydrochloric Acid SCHEMBL6366795 | 0.80 | F2 (0.44) | ST14F2MASP2PROCPRSS1 | |
| Hydrochloric Acid SCHEMBL6366417 | 0.79 | ST14 (0.46) | ST14F2MASP2PRSS1TMPRSS15 | |
| Hydrochloric Acid SCHEMBL6365556 | 0.79 | ST14 (0.46) | ST14F2MASP2PROCPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206444-B1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | MORPHOCHEM AG (DE) | 2003-11-12 | — | — | EP | disclosed |