Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.54 |
| ▸ | F7 | P08709 | 5/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.42 |
| ▸ | SFN | P31947 | 2/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6365976 | 0.99 | ST14 (0.53) | ST14F7ADRA1BF2ITGB3 | |
| Hydrochloric Acid SCHEMBL6365784 | 0.91 | ST14 (0.53) | ST14F7ADRA1BF2ITGB3 | |
| SCHEMBL7116195 | 0.86 | ST14 (0.55) | ST14F7F2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL7539002 | 0.85 | ST14 (0.54) | ST14F7F2ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL6372117 | 0.82 | KMT2A (0.44) | ST14F2MASP2F10NPC1 | |
| SCHEMBL7428875 | 0.82 | ABCG2 (0.37) | SFNKDM4EF13A1 | |
| Hydrochloric Acid SCHEMBL6367551 | 0.81 | TPSAB1 (0.60) | ST14F7F2MASP2F10 | |
| Hydrochloric Acid SCHEMBL6372032 | 0.80 | ST14 (0.61) | ST14F7ADRA1BF2ITGB3 | |
| Hydrochloric Acid SCHEMBL6366354 | 0.80 | F7 (0.44) | ST14F7ADRA1BF2F10 | |
| Hydrochloric Acid SCHEMBL6364925 | 0.79 | ITGB3 (0.46) | ST14F2ITGB3ITGA2BSFN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206444-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | Morphochem AG (DE) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014320-A1 | COMPOUNDS THAT INHIBIT TRYPTASE ACTIVITY | MORPHOCHEM AG (DE) | 2001-03-01 | — | — | WO | disclosed |